FzM1

Product Name: FzM1
CAS No.: 1680196-54-6
Chemical Name: FzM1
Synonyms: FzM1;FzM1 >=98% (HPLC);FzM1, 10 mM in DMSO;FzM1 (Fzd4 modulator FzM1;N-[3-hydroxy-5-(2-thienyl)phenyl]-N'-2-naphthalenyl-urea;Urea, N-[3-hydroxy-5-(2-thienyl)phenyl]-N'-2-naphthalenyl-;1-(3-Hydroxy-5-(thiophen-2-yl)phenyl)-3-(naphthalen-2-yl)urea
CBNumber: CB63152616
Molecular Formula: C21H16N2O2S
Formula Weight: 360.43
MOL File: 1680196-54-6.mol

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FzM1 Property

Boiling point:: 518.3±50.0 °C(Predicted)
Density: 1.401±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 12 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.2 mg/ml; DMSO: 10 mg/ml
form: A crystalline solid
pka: 9.42±0.10(Predicted)
color: White to light brown

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 19074
Product name: FzM1
Purity: ≥95%
Packaging: 500μg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 19074
Product name: FzM1
Purity: ≥95%
Packaging: 1mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 19074
Product name: FzM1
Purity: ≥95%
Packaging: 5mg
Price: $118
Updated: 2024/03/01

AK Scientific

Product number: SYN5597
Product name: FzM1
Packaging: 10mg
Price: $160
Updated: 2021/12/16

AK Scientific

Product number: SYN5597
Product name: FzM1
Packaging: 50mg
Price: $547
Updated: 2021/12/16

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FzM1 Chemical Properties,Usage,Production

Description

Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis. Wnt proteins initiate cell signaling by binding Frizzled (Fz) receptors, a family of G protein-coupled receptors. FzM1 is an allosteric ligand of Fz4. At 10 μM, it inhibits nuclear translocation of β-catenin in U87MG glioma cells treated with lithium chloride, a GSK3 inhibitor that enhances the Wnt canonical signaling pathway. FzM1 impairs the ability of U87MG cells to form neurospheres in culture and stimulates the differentiation of Caco-2 epithelial colorectal adenocarcinoma cells.

FzM1 Preparation Products And Raw materials

Raw materials

Preparation Products

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FzM1 Suppliers

China 20 United States 2 Global 22

Shanghai EFE Biological Technology Co., Ltd.

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HANGZHOU CLAP TECHNOLOGY CO.,LTD

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Energy Chemical

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MedBioPharmaceutical Technology Inc

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RD International Technology Co., Limited

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Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd

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Neobioscience Co., Ltd.

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Absin Bioscience Inc.

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Proteintech China

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Shanghai Hao Zhun Biological Technology Co., Ltd.

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1680196-54-6, FzM1Related Search:

FzM1

FzM1 (Fzd4 modulator FzM1

FzM1 >=98% (HPLC)

Urea, N-[3-hydroxy-5-(2-thienyl)phenyl]-N'-2-naphthalenyl-

N-[3-hydroxy-5-(2-thienyl)phenyl]-N'-2-naphthalenyl-urea

1-(3-Hydroxy-5-(thiophen-2-yl)phenyl)-3-(naphthalen-2-yl)urea

FzM1, 10 mM in DMSO

1680196-54-6