ChemicalBook > CAS DataBase List > FzM1
FzM1
- Product Name
- FzM1
- CAS No.
- 1680196-54-6
- Chemical Name
- FzM1
- Synonyms
- FzM1;FzM1 >=98% (HPLC);FzM1, 10 mM in DMSO;FzM1 (Fzd4 modulator FzM1;N-[3-hydroxy-5-(2-thienyl)phenyl]-N'-2-naphthalenyl-urea;Urea, N-[3-hydroxy-5-(2-thienyl)phenyl]-N'-2-naphthalenyl-;1-(3-Hydroxy-5-(thiophen-2-yl)phenyl)-3-(naphthalen-2-yl)urea
- CBNumber
- CB63152616
- Molecular Formula
- C21H16N2O2S
- Formula Weight
- 360.43
- MOL File
- 1680196-54-6.mol
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FzM1 Property
- Boiling point:
- 518.3±50.0 °C(Predicted)
- Density
- 1.401±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 12 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.2 mg/ml; DMSO: 10 mg/ml
- form
- A crystalline solid
- pka
- 9.42±0.10(Predicted)
- color
- White to light brown
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 19074
- Product name
- FzM1
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $37
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 19074
- Product name
- FzM1
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $68
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 19074
- Product name
- FzM1
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $118
- Updated
- 2024/03/01
AK Scientific
- Product number
- SYN5597
- Product name
- FzM1
- Packaging
- 10mg
- Price
- $160
- Updated
- 2021/12/16
AK Scientific
- Product number
- SYN5597
- Product name
- FzM1
- Packaging
- 50mg
- Price
- $547
- Updated
- 2021/12/16
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FzM1 Chemical Properties,Usage,Production
Description
Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis. Wnt proteins initiate cell signaling by binding Frizzled (Fz) receptors, a family of G protein-coupled receptors. FzM1 is an allosteric ligand of Fz4. At 10 μM, it inhibits nuclear translocation of β-catenin in U87MG glioma cells treated with lithium chloride, a GSK3 inhibitor that enhances the Wnt canonical signaling pathway. FzM1 impairs the ability of U87MG cells to form neurospheres in culture and stimulates the differentiation of Caco-2 epithelial colorectal adenocarcinoma cells.
FzM1 Preparation Products And Raw materials
Raw materials
Preparation Products
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FzM1 Suppliers
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32161
- Advantage
- 58
- Tel
- --
- Fax
- --
- cayman@caymanchem.com
- Country
- United States
- ProdList
- 6213
- Advantage
- 81