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BAR 501 impurity

Product Name
BAR 501 impurity
CAS No.
1632118-70-7
Chemical Name
BAR 501 impurity
Synonyms
BAR 501 impurity;BAR 501 impurity, 10 mM in DMSO;Cholane-3,7,24-triol, 6-ethyl-, (3α,5β,6β,7α)-;(3alpha,5beta,6beta,7alpha)-6-Ethylcholane-3,7,24-triol;(3R,5S,6S,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-17-[(2R)-5-hydroxypentan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
CBNumber
CB63160019
Molecular Formula
C26H46O3
Formula Weight
406.64
MOL File
1632118-70-7.mol
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BAR 501 impurity Property

Boiling point:
527.6±25.0 °C(Predicted)
Density 
1.047±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 20 mg/mL; DMSO: 100μg/ml; Ethanol: 2 mg/mL; Ethanol:PBS (pH 7.2)(1:2): 500μg/ml
form 
A crystalline solid
pka
14.82±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22461
Product name
BAR501 Impurity
Purity
≥95%
Packaging
1mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
22461
Product name
BAR501 Impurity
Purity
≥95%
Packaging
5mg
Price
$233
Updated
2024/03/01
Cayman Chemical
Product number
22461
Product name
BAR501 Impurity
Purity
≥95%
Packaging
10mg
Price
$437
Updated
2024/03/01
Biosynth Carbosynth
Product number
BB178033
Product name
BAR 501 impurity
Packaging
50mg
Price
$450
Updated
2021/12/16
Biosynth Carbosynth
Product number
BB178033
Product name
BAR 501 impurity
Packaging
100mg
Price
$650
Updated
2021/12/16
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BAR 501 impurity Chemical Properties,Usage,Production

Description

BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501 impurity (10 μM) induces a 150% increase in luciferase activity in a GP-BAR1 reporter gene assay.1

References

1. Festa, C., Renga, B., D'Amore, C., et al. Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands J. Med. Chem. 57(20),8477-8495(2014).

BAR 501 impurity Preparation Products And Raw materials

Raw materials

Preparation Products

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BAR 501 impurity Suppliers

China 19 United States 4 Global 23
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185 18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3466
Advantage
58
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai Biopharmaleader Co., Ltd.
Tel
+86 18721201413
Fax
+86 (21) 5775-8967
Email
sales@biopharmaleader.com
Country
China
ProdList
1720
Advantage
58
Jinan Yaoyan Pharmaceutical Co., Ltd.
Tel
Fax
-
Email
jnyaoyan@163.com
Country
China
ProdList
3069
Advantage
58
Aishilun biotechnology (Shanghai) co., LTD
Tel
021-50676523 18019098996
Email
info@acelybio.com
Country
China
ProdList
3960
Advantage
58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19103
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
Advantage
58
Changzhou Chenhong Biotechnology Co., Ltd.
Tel
0519-85788828 13775037613
Email
sales@chemrenpharm.com
Country
China
ProdList
3600
Advantage
58

1632118-70-7, BAR 501 impurityRelated Search:


  • BAR 501 impurity
  • (3R,5S,6S,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-17-[(2R)-5-hydroxypentan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
  • (3alpha,5beta,6beta,7alpha)-6-Ethylcholane-3,7,24-triol
  • Cholane-3,7,24-triol, 6-ethyl-, (3α,5β,6β,7α)-
  • BAR 501 impurity, 10 mM in DMSO
  • 1632118-70-7