ChemicalBook > CAS DataBase List > HO-PEG10-CH2CH2COOH
HO-PEG10-CH2CH2COOH
- Product Name
- HO-PEG10-CH2CH2COOH
- CAS No.
- 2375611-66-6
- Chemical Name
- HO-PEG10-CH2CH2COOH
- Synonyms
- HO-PEG10-CH2CH2COOH;1-Hydroxy-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oic acid;Propanoic acid, 3-[(29-hydroxy-3,6,9,12,15,18,21,24,27-nonaoxanonacos-1-yl)oxy]-;PROTAC Linkers,ADC Linkers,Inhibitor,inhibit,Hydroxy PEG10 acid,Antibody-drug conjugates linkers,Hydroxy-PEG-10-acid,HydroxyPEG10acid
- CBNumber
- CB63309421
- Molecular Formula
- C23H46O13
- Formula Weight
- 530.6
- MOL File
- 2375611-66-6.mol
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HO-PEG10-CH2CH2COOH Property
- Boiling point:
- 614.7±55.0 °C(Predicted)
- Density
- 1.143±0.06 g/cm3(Predicted)
- pka
- 4.28±0.10(Predicted)
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HO-PEG10-CH2CH2COOH Chemical Properties,Usage,Production
Biological Activity
Hydroxy-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
HO-PEG10-CH2CH2COOH Preparation Products And Raw materials
Raw materials
Preparation Products
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HO-PEG10-CH2CH2COOH Suppliers
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View Lastest Price from HO-PEG10-CH2CH2COOH manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Hydroxy-PEG10-acid 2375611-66-6
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-25