2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid
- Product Name
- 2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid
- CAS No.
- 944561-45-9
- Chemical Name
- 2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid
- Synonyms
- Propynyl-PEG1-Ac;Propargyl-PEG1-CH2COOH;Propargyl-PEG1-acetic Acid;2-(2-prop-2-ynoxyethoxy)acetic acid;2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid;Acetic acid, 2-[2-(2-propyn-1-yloxy)ethoxy]-
- CBNumber
- CB63975392
- Molecular Formula
- C7H10O4
- Formula Weight
- 158.15
- MOL File
- 944561-45-9.mol
2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid Property
- Boiling point:
- 294.2±20.0 °C(Predicted)
- Density
- 1.169±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- pka
- 3.37±0.10(Predicted)
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- AS104180
- Product name
- 2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $294
- Updated
- 2021/12/16
- Product number
- 0351EB
- Product name
- 2-[2-(2-Propyn-1-yloxy)ethoxy]aceticacid
- Packaging
- 100mg
- Price
- $310
- Updated
- 2021/12/16
- Product number
- AS104180
- Product name
- 2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $585
- Updated
- 2021/12/16
- Product number
- 0351EB
- Product name
- 2-[2-(2-Propyn-1-yloxy)ethoxy]aceticacid
- Packaging
- 2.5g
- Price
- $1535
- Updated
- 2021/12/16
- Product number
- 0351EB
- Product name
- 2-[2-(2-Propyn-1-yloxy)ethoxy]aceticacid
- Packaging
- 5g
- Price
- $2222
- Updated
- 2021/12/16
2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid Chemical Properties,Usage,Production
Uses
Propynyl-PEG1-Ac is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propynyl-PEG1-Ac is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid Suppliers
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