ChemicalBook > CAS DataBase List > RBC10
RBC10
- Product Name
- RBC10
- CAS No.
- 362503-73-9
- Chemical Name
- RBC10
- Synonyms
- RBC10;RBC10, 10 mM in DMSO;inhibit,Ras,anti-cancer,RBC10,Ral,Inhibitor,RALBP1,embryonic fibroblasts,growth;11-(2-Chlorophenyl)-10-pentanoyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one;11-(2-Chlorophenyl)-2,3,4,5,10,11-hexahydro-10-(1-oxopentyl)-1H-dibenzo[b,e][1,4]diazepin-1-one;1H-Dibenzo[b,e][1,4]diazepin-1-one, 11-(2-chlorophenyl)-2,3,4,5,10,11-hexahydro-10-(1-oxopentyl)-;RBC10 1-(3-acetyl-2-(2-chlorophenyl)-4-methyl-2,5-dihydro-1H-benzo[b][1,4]diazepin-1-yl)pentan-1-one
- CBNumber
- CB64200323
- Molecular Formula
- C24H25ClN2O2
- Formula Weight
- 408.92
- MOL File
- 362503-73-9.mol
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RBC10 Property
- storage temp.
- Store at -20°C
- solubility
- DMSO : 125 mg/mL (305.68 mM; Need ultrasonic)
- form
- Solid
- color
- White to off-white
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RBC10 Chemical Properties,Usage,Production
Uses
RBC10 is an anti-cancer agent. RBC10 inhibits the binding of Ral to its effector RALBP1. RBC10 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines[1].
References
[1] Yan C, et al. Discovery and characterization of small molecules that target the GTPase Ral. Nature. 2014;515(7527):443-447. DOI:10.1038/nature13713
RBC10 Preparation Products And Raw materials
Raw materials
Preparation Products
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