CLIP (86-100)
- Product Name
- CLIP (86-100)
- CAS No.
- 648881-58-7
- Chemical Name
- CLIP (86-100)
- Synonyms
- CLIP (86-100);L-Alanine, L-prolyl-L-valyl-L-seryl-L-lysyl-L-methionyl-L-arginyl-L-methionyl-L-alanyl-L-threonyl-L-prolyl-L-leucyl-L-leucyl-L-methionyl-L-glutaminyl-
- CBNumber
- CB64713670
- Molecular Formula
- C72H128N20O19S3
- Formula Weight
- 1674.1
- MOL File
- 648881-58-7.mol
CLIP (86-100) Property
- Density
- 1.42±0.1 g/cm3(Predicted)
- pka
- 3.39±0.10(Predicted)
- form
- Solid
- color
- White to off-white
- Sequence
- Pro-Val-Ser-Lys-Met-Arg-Met-Ala-Thr-Pro-Leu-Leu-Met-Gln-Ala
CLIP (86-100) Chemical Properties,Usage,Production
Uses
CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site[1].
References
[1] van Luijn MM, et al. Class II-associated invariant chain peptide as predictive immune marker in minimal residual disease in acute myeloid leukemia. Oncoimmunology. 2015 Jan 7;3(12):e941737. eCollection 2014 Dec. DOI:10.4161/21624011.2014.941737
[2] Thayer WP, et al. Class II-associated invariant chain peptide-independent binding of invariant chain to class II MHC molecules. J Immunol. 1999 Feb 1;162(3):1502-9. PMID:9973407
CLIP (86-100) Preparation Products And Raw materials
Raw materials
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