Methyl 5-thiazolecarboxylate
- Product Name
- Methyl 5-thiazolecarboxylate
- CAS No.
- 14527-44-7
- Chemical Name
- Methyl 5-thiazolecarboxylate
- Synonyms
- NSC 321257;RARECHEM AL BF 1261;Methyl 5-thiazolecar;5-thiazole carboxylate.;METHYL 5-THIAZOLECARBOXYLATE;METHYL THIAZOLE-5-CARBOXYLATE;5-(Methoxycarbonyl)-1,3-thiazole;methyl 1,3-thiazole-5-carboxylate;Methyl 1,3-thiazole-5-carboxylate 98%;Thiazole-5-carboxylic acid methyl ester
- CBNumber
- CB6481766
- Molecular Formula
- C5H5NO2S
- Formula Weight
- 143.16
- MOL File
- 14527-44-7.mol
Methyl 5-thiazolecarboxylate Property
- Melting point:
- 68-69°C
- Boiling point:
- 87-90°C (10 mmHg)
- Density
- 1.45
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 0.80±0.10(Predicted)
- Appearance
- Off-white to light yellow Solid
- CAS DataBase Reference
- 14527-44-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36/37/39
- Hazard Note
- Harmful
- HS Code
- 2934100090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- M331478
- Product name
- MethylThiazole-5-carboxylate
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 8H70-1-V8
- Product name
- Methyl 1,3-thiazole-5-carboxylate
- Packaging
- 1g
- Price
- $105
- Updated
- 2021/12/16
- Product number
- 8H70-1-V8
- Product name
- Methyl 1,3-thiazole-5-carboxylate
- Packaging
- 250mg
- Price
- $35
- Updated
- 2021/12/16
- Product number
- C222
- Product name
- Methylthiazole-5-carboxylate
- Packaging
- 1g
- Price
- $40
- Updated
- 2021/12/16
- Product number
- CS-M1604
- Product name
- 5-Thiazolecarboxylicacid,methylester
- Packaging
- 5g
- Price
- $129
- Updated
- 2021/12/16
Methyl 5-thiazolecarboxylate Chemical Properties,Usage,Production
Synthesis
6633-61-0
14527-44-7
The general procedure for the synthesis of methyl 5-thiazolecarboxylate from methyl 2-aminothiazole-5-carboxylate was as follows: a mixture of 2.25 g of isoamyl nitrite with 10 mL of dioxane was stirred at 80 °C under nitrogen protection. Subsequently, a 20 mL dioxane solution containing 1.23 g of methyl 2-aminothiazole-5-carboxylate (g-3) was slowly added dropwise. After the dropwise addition was completed, the reaction mixture was refluxed for 2 hours. After the reaction was completed, it was cooled to room temperature and diluted by adding 30 mL of ethyl acetate. The organic phase was washed with saturated saline, dried over anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography to give 0.54 g (48% yield) of the target product methyl 5-thiazolecarboxylate (g-4).
References
[1] Patent: WO2003/97616, 2003, A1. Location in patent: Page/Page column 26
Methyl 5-thiazolecarboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl 5-thiazolecarboxylate manufacturers
- Product
- Methyl 5-thiazolecarboxylate 14527-44-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-26