ChemicalBook > CAS DataBase List > AC-DEVD-CHO

AC-DEVD-CHO

Product Name
AC-DEVD-CHO
CAS No.
169332-60-9
Chemical Name
AC-DEVD-CHO
Synonyms
MF 191;AC-DEVD-CHO;AC-DEVD-ALDEHYDE;AC-DEVD-CHO?, >98%;CASPASE-3 INHIBITOR;Ac-DEVD-CHO acetate;ACETYL-DEVD-ALDEHYDE;Ac-Asp-Glu-Val-Asp-H;CASPASE-3 INHIBITOR I;AC-DEVD-CHO USP/EP/BP
CBNumber
CB6488321
Molecular Formula
C20H30N4O11
Formula Weight
502.47
MOL File
169332-60-9.mol
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AC-DEVD-CHO Property

Boiling point:
1021.1±65.0 °C(Predicted)
Density 
1.374±0.06 g/cm3(Predicted)
RTECS 
EK7643000
storage temp. 
-20°C
solubility 
H2O: 1 mg/mL
pka
4.19±0.10(Predicted)
form 
powder
color 
white
biological source
synthetic
Water Solubility 
H2O: 1mg/mL
Sensitive 
Moisture Sensitive
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
235420
Product name
Caspase-3 Inhibitor I
Packaging
1mg
Price
$113
Updated
2024/03/01
Sigma-Aldrich
Product number
235420
Product name
Caspase-3 Inhibitor I
Packaging
5mg
Price
$475
Updated
2024/03/01
Alfa Aesar
Product number
J65204
Product name
N-Acetyl-Asp-Glu-Val-Asp-al
Packaging
5mg
Price
$401
Updated
2023/06/20
Alfa Aesar
Product number
J65204
Product name
N-Acetyl-Asp-Glu-Val-Asp-al
Packaging
1mg
Price
$101
Updated
2021/12/16
Sigma-Aldrich
Product number
A0835
Product name
N-Acetyl-Asp-Glu-Val-Asp-al
Purity
≥95%, powder
Packaging
1mg
Price
$161
Updated
2024/03/01
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AC-DEVD-CHO Chemical Properties,Usage,Production

Uses

Reversible inhibitor of interleukin-1beta converting enzyme (ICE); also inhibits caspase-3 cleavage of poly(ADP-ribose) polymerase

Uses

N-Acetyl-Asp-Glu-Val-Asp-al has been used as a caspase inhibitor in muscle samples, smooth muscle cells and Jurkat T-cells.

Definition

ChEBI: A tetrapeptide consisting of two L-aspartic acid residues, an L-glutamyl residue and an L-valine residue with an acetyl group at the N-terminal and with the C-terminal carboxy group reduced to an aldehyde. It is an inhibitor of caspase-3/7.

General Description

N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) is a tetrapeptide with N-terminal acetylation and C-terminal aldehyde conjugation.

Biochem/physiol Actions

N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) aids in the recovery of stunned myocardium by its caspase inhibition functionality.

AC-DEVD-CHO Preparation Products And Raw materials

Raw materials

Preparation Products

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AC-DEVD-CHO Suppliers

China 65 India 1 Switzerland 1 United Kingdom 2 United States 15 Global 84
VDM Biochemicals
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169332-60-9, AC-DEVD-CHORelated Search:

AC-IETD-CHO N-acetyl aspartyl-glutaMic acid AC-DEVD-CHO BIOTIN-ASP(OME)-GLU(OME)-VAL-ASP(OME)-FLUOROMETHYLKETONE AC-DEVD-AMC ORCOKININ AC-DEVD-AFC AC-DEVD-CHO BIOTIN-DEVD-CHO MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH AC-DEVD-PNA CYCLIC ADIPOYL-(6-AMINO)HEXANOYL-DEVD-RHODAMINE 110, TRIETHYLAMINE SALT BIOTIN-X-DEVD-FMK (7-METHOXYCOUMARIN-4-YL)ACETYL-L-ASPARTYL-L-GLUTAMYL-L-VALYL-L-ASPARTYL-L-ALANYL-L-PROLYL-N-EPSILON-(2,4-DINITROPHENYL)-L-LYSINE AMIDE AC-ASP-GLU-VAL-ASP-BETA-NA BIOTINYL-ASP(OME)-GLU(OME)-VAL-ASP(OME)-FLUOROMETHYLKETONE ANTI-IP3 RECEPTOR TYPE I NEUTRALIZING PEPTIDE AC-ASP-GLU-VAL-ASP-CHO TFA

  • Ac-DEVD-CHO,N-Acetyl-Asp-Glu-Val-Asp-al, >98%
  • AC-DEVD-CHO?, >98%
  • Caspase-3 Inhibitor I - CAS 169332-60-9 - Calbiochem
  • N-ACETYL-L-ALPHA-ASPARTYL-L-ALPHA-GLUTAMYL-N-(2-CARBOXY-1-FORMYLETHYL)-L VALINAMIDE
  • N-AC-ASP-GLU-VAL-ASP-CHO
  • N-ACETYL-ASP-GLU-VAL-ASP-AL
  • N-ACETYL-ASP-GLU-VAL-ASP-CHO (ALDEHYDE)
  • CPP32/APOPAIN INHIBITOR
  • CASPASE-3 INHIBITOR I
  • CASPASE-3 INHIBITOR (ALDEHYDE)
  • ACETYL-DEVD-ALDEHYDE
  • ACETYL-L-ASPARTYL-L-GLUTAMYL-L-VALYL-L-ASPART-1-AL
  • ACETYL-ASP-GLU-VAL-ASP-ALDEHYDE
  • AC-DEVD-CHO
  • AC-DEVD-ALDEHYDE
  • AC-ASP-GLU-VAL-ASP-ALDEHYDE
  • AC-ASP-GLU-VAL-ASP-ALDEHYDE (PSEUDO ACID)
  • AC-ASP-GLU-VAL-ASP-H (ALDEHYDE)
  • AC-ASP-GLU-VAL-ASP-CHO
  • Acetyl-aspartyl-glutamyl-valyl-aspartal
  • CASPASE-3 INHIBITOR
  • CASPASE 3 (APOPAIN) INHIBITOR 1
  • MF 191
  • N-acetyl-Asp-Glu-Val-Asp-Ala
  • (4S,7S,10S,13S)-7-(2-carboxyethyl)-4-(carboxyMethyl)-13-forMyl-10-isopropyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid
  • Ac-Asp-Glu-Val-Asp-H
  • CASPASE-3 INHIBITOR I;N-AC-ASP-GLU-VAL-ASP-CHO;ACETYL-ASPARTYL-GLUTAMYL-VALYL-ASPARTAL
  • L-Valinamide, N-acetyl-L-α-aspartyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-
  • N-Acetyl-Asp-Glu-Val-Asp-al >=95%, powder
  • AC-DEVD-CHO USP/EP/BP
  • Ac-DEVD-CHO，N-Acetyl-Asp-Glu-Val-Asp-al
  • Caspase 3 Inhibitor I,Caspase3 Inhibitor I
  • AcDEVDCHO,Ac DEVD CHO
  • Ac-DEVD-CHO acetate
  • 169332-60-9
  • Caspase 10
  • Caspases
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Apoptosis and Cell Cycle
  • BioChemical
  • Inhibitors
  • peptides
  • Caspase 10
  • Caspase 3
  • Caspase 7
  • Caspase 8
  • Caspase Inhibitors
  • Caspase Inhibitors and Substrates
  • Peptides and Proteins
  • Peptides for Cell Biology
  • Protease Inhibitor Specificity Index
  • Protease Inhibitors
  • A to C
  • A-AM
  • Aldehydes
  • and Substrates
  • Apoptosis and Cell Cycle