guselkumab

Product Name: guselkumab
CAS No.: 1350289-85-8
Chemical Name: guselkumab
Synonyms: CNTO 1959;guselkumab;Guselkumab (anti-IL-23);Research Grade Guselkumab;Research Grade Guselkumab(DHJ63103)
CBNumber: CB64919948
Formula Weight: 0
MOL File: Mol file

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guselkumab Property

storage temp.: Store at -20°C
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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guselkumab Chemical Properties,Usage,Production

Uses

Guselkumab is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab binds to human and cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research[1].

IC 50

IL-23: .06 nM (IC₅₀)

References

[1] International non-proprietary name: guselkumab Procedure No. EMEA/H/C/004271/0000par-public-assessment-report_en.pdf
[2] Li Li, et al. IBI112, a selective anti-IL23p19 monoclonal antibody, displays high efficacy in IL-23-induced psoriasiform dermatitis. Int Immunopharmacol DOI:10.1016/j.intimp.2020.107008

guselkumab Preparation Products And Raw materials

Raw materials

Preparation Products

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guselkumab Suppliers

China 26 United States 2 USA 1 Global 29

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
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ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
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Shanghai Zhibang Biological Medicine Co., LTD

Tel: 021-54285032 18116461626
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Country: China
ProdList: 148
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
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Guangzhou Hongyuan Chemical Co.,Ltd

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Wuhan Dingxintong Pharmaceutical Co. , Ltd.

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Wuhan Chemstan Biotechnology Co., Ltd.

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Bide Pharmatech Ltd.

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Shaanxi DIDU pharmaceutical and Chemical Co., Ltd

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TargetMol Chemicals Inc.

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1350289-85-8, guselkumabRelated Search:

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guselkumab

Research Grade Guselkumab(DHJ63103)

Guselkumab (anti-IL-23)

CNTO 1959

Research Grade Guselkumab

1350289-85-8