Thalidomide-4-O-C8-NH2

Product Name: Thalidomide-4-O-C8-NH2
CAS No.: 1957235-91-4
Chemical Name: Thalidomide-4-O-C8-NH2
Synonyms: Thalidomide-O-C8-NH2;Thalidomide-4-O-C8-NH2;4-((8-Aminooctyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl;4-[(8-Aminooctyl)oxy]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione;1H-Isoindole-1,3(2H)-dione, 4-[(8-aminooctyl)oxy]-2-(2,6-dioxo-3-piperidinyl)-;4-[(8-aminooctyl)oxy]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
CBNumber: CB66215684
Molecular Formula: C21H27N3O5
Formula Weight: 401.46
MOL File: 1957235-91-4.mol

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Thalidomide-4-O-C8-NH2 Property

Boiling point:: 639.9±55.0 °C(Predicted)
Density: 1.274±0.06 g/cm3(Predicted)
pka: 10.70±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS106297
Product name: 4-(8-Aminooctyloxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dioneHCl
Purity: 97%
Packaging: 100mg
Price: $413
Updated: 2021/12/16

Acrotein

Product number: AS01451
Product name: 4-(8-Aminooctyloxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dioneHCl
Purity: 97%
Packaging: 0.25g
Price: $586.67
Updated: 2021/12/16

Acrotein

Product number: AS01451
Product name: 4-(8-Aminooctyloxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dioneHCl
Purity: 97%
Packaging: 0.1g
Price: $293.33
Updated: 2021/12/16

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Thalidomide-4-O-C8-NH2 Chemical Properties,Usage,Production

Uses

Thalidomide-4-O-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC 50

Cereblon

References

[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1008. DOI:10.1016/j.cell.2020.07.024

Thalidomide-4-O-C8-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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Thalidomide-4-O-C8-NH2 Suppliers

China 8 Global 8

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
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Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
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ProdList: 1615
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Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD

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ShenZhen Trendseen Biological Technology Co.,Ltd.

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Shanghai Easy CDMO Co.,Ltd

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Email: info@easycdmo.com
Country: China
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Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD

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Jilin Chinese Academy of Sciences-yanshen Technology

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Biosynth Biological Technology (Suzhou) Co Ltd

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Country: China
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1957235-91-4, Thalidomide-4-O-C8-NH2 Related Search:

Thalidomide-O-C6-NH2 Thalidomide-O-C6-NH2 TFA Pentanoic acid, 5-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Thalidomide-O-C5-NH2 Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Thalidomide-O-PEG4-amine Thalidomide-O-PEG4-NHS ester 4-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione Thalidomide-O-PEG3-amine HCl Acetamide, N-[2-[3-[3-(2-aminoethoxy)propoxy]propoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Thalidomide-O-PEG4-azide Thalidomide-O-C3-acid Thalidomide-O-C5-acid Thalidomide-NH-PEG2-C2-NH2 (TFA) 5-[[2-(2-aminoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione, Pentanoic acid, 5-[[2-(2,6-dioxo-3-piperidinyl)- 2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]- 1H-Isoindole-1,3(2H)-dione, 4-(3-aminopropoxy)-2-(2,6-dioxo-3-piperidinyl)- 5-[(8-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione,

4-((8-Aminooctyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl

Thalidomide-O-C8-NH2

1H-Isoindole-1,3(2H)-dione, 4-[(8-aminooctyl)oxy]-2-(2,6-dioxo-3-piperidinyl)-

Thalidomide-4-O-C8-NH2

4-[(8-Aminooctyl)oxy]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione

4-[(8-aminooctyl)oxy]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione

1957235-91-4