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Cefcapene

Product Name
Cefcapene
CAS No.
135889-00-8
Chemical Name
Cefcapene
Synonyms
CEFCAPENE;s1006;Cefcamate;Cefcarpinic Acid;CEFCAPENE Impurity;Cefcapene Impurity 5;Cefcapene Impurity 7;Cefcapene pivoxil free acid;Cefcapene Pivoxil Impurity 1;Cefcapene pivoxil Impurity 16
CBNumber
CB6680909
Molecular Formula
C17H19N5O6S2
Formula Weight
453.49
MOL File
135889-00-8.mol
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Cefcapene Property

Boiling point:
936.0±65.0 °C(Predicted)
Density 
1.63
pka
2.58±0.50(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
C242545
Product name
Cefcapene
Packaging
25mg
Price
$4125
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007951
Product name
CEFCAPENE
Purity
95.00%
Packaging
25MG
Price
$4908.75
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007951
Product name
CEFCAPENE
Purity
95.00%
Packaging
1MG
Price
$925.05
Updated
2021/12/16
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Cefcapene Chemical Properties,Usage,Production

Uses

Cefcapene is a metabolite of Cefcapene Pivoxil (C242550). Antibacterial, orally absorbed cephalosporin that is used in the treatment of bacterial infections.

Definition

ChEBI: Cefcapene is a cephalosporin compound having (carbamoyloxy)methyl and N-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino side-groups. It is used (generally as the corresponnding pivaloyloxymethyl ester prodrug) as an oral antibacterial. It has a role as an antibacterial drug. It is a cephalosporin, a carboxylic acid, a carbamate ester, an enamide, a member of 1,3-thiazoles and a secondary carboxamide.

Antimicrobial activity

A semisynthetic cephalosporin formulated for oral administration as the prodrug ester, cefcapene pivoxil. Activity and uses are similar to those of cefditoren.
Available in Japan.

Pharmacokinetics

Cefcapene is a semisynthetic third-generation cephalosporin with antibacterial activity. Cefcapene binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
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Cefcapene Preparation Products And Raw materials

Raw materials

Preparation Products

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Cefcapene Suppliers

TOSUN PHARM
Tel
020-61855200 13326451905
Email
2881290884@qq.com
Country
China
ProdList
7538
Advantage
58
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15421
Advantage
60
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-83725681-603
Fax
+86 755 28094224
Country
China
ProdList
4505
Advantage
50
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12338
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9900
Advantage
58
Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9685
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17993
Advantage
56
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9767
Advantage
58
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View Lastest Price from Cefcapene manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Cefcapene 135889-00-8
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-04-25
Career Henan Chemical Co
Product
(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 135889-00-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-09-04

135889-00-8, CefcapeneRelated Search:


  • CEFCAPENE
  • s1006
  • (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-pentenoylamino]-8-oxo-3-(carbamoyloxymethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (7R)-7-[[(Z)-2-(2-Amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-3-[(carbamoyloxy)methyl]cepham-3-ene-4-carboxylic acid
  • Cefcamate
  • Cefcapene pivoxil free acid
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aMinocarbonyl)oxy]Methyl]-7-[[(2Z)-2-(2-aMino-4-thiazolyl)-1-oxo-2-penten-1-yl]aMino]-8-oxo-,(6R,7R)-
  • (6R,7R)-3-[[(AMinocarbonyl)oxy]Methyl]-7-[[(2Z)-2-(2-aMino-4-thiazolyl)-1-oxo-2-penten-1-yl]aMino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
  • (6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic
  • Cefcapene Impurity 5
  • Cefcapene Pivoxil Impurity 1
  • Cefcapene Pivoxil Impurity 4 (Cefcapene)
  • Cefcapene Impurity 7
  • (6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicaci
  • Cefcarpinic Acid
  • Cefcapene pivoxil Impurity 16
  • CEFCAPENE Impurity
  • 135889-00-8
  • C23H29N5O8S2
  • C17H19N5O6S2
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Sulfur & Selenium Compounds