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ChemicalBook > CAS DataBase List > 4-Methyl-1-piperazineethanamine

4-Methyl-1-piperazineethanamine

Uses
Product Name
4-Methyl-1-piperazineethanamine
CAS No.
934-98-5
Chemical Name
4-Methyl-1-piperazineethanamine
Synonyms
AKOS BB-6128;CHEMBRDG-BB 4006383;4-Methylpiperazin-1-ethylamin;4-methylpiperazine-1-ethylamine;4-METHYL-1-PIPERAZINEETHANAMINE;1-(2-AMINOETHYL)METHYLPIPERAZINE;1-Piperazineethanamine, 4-methyl-;1-(2-Aminoethyl)-4-methyl-piperaz;1-Methyl-4-(2-aminoethyl)piperazine;2-(4-METHYLPIPERAZIN-1-YL)ETHANAMINE
CBNumber
CB6721134
Molecular Formula
C7H17N3
Formula Weight
143.23
MOL File
934-98-5.mol
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4-Methyl-1-piperazineethanamine Property

Boiling point:
103°C/11.25mm
Density 
0.956±0.06 g/cm3(Predicted)
refractive index 
1.4780
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
liquid
pka
10.11±0.10(Predicted)
color 
Colourless to light yellow
Sensitive 
Air Sensitive
InChI
InChI=1S/C7H17N3/c1-9-4-6-10(3-2-8)7-5-9/h2-8H2,1H3
InChIKey
GOWUDHPKGOIDIX-UHFFFAOYSA-N
SMILES
N1(CCN)CCN(C)CC1
CAS DataBase Reference
934-98-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36/37/39
RIDADR 
2735
Hazard Note 
Irritant
HazardClass 
8
PackingGroup 
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS003000
Product name
2-(4-Methyl-piperazin-1-yl)-ethylamine
Purity
AldrichCPR
Packaging
250MG
Price
$87.5
Updated
2025/07/31
TCI Chemical
Product number
M3597
Product name
2-(4-Methylpiperazin-1-yl)ethan-1-amine
Purity
min. 95.0 %
Packaging
1G
Price
$63
Updated
2025/07/31
TRC
Product number
M725980
Product name
2-(4-Methylpiperazin-1-yl)ethanamine
Packaging
2.5g
Price
$130
Updated
2021/12/16
Apolloscientific
Product number
OR0800
Product name
1-(2-Aminoethyl)-4-methylpiperazine
Purity
95%
Packaging
5g
Price
$106
Updated
2021/12/16
Oakwood
Product number
030836
Product name
2-(4-Methyl-piperazin-1-yl)-ethylamine
Packaging
5g
Price
$89
Updated
2021/12/16
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4-Methyl-1-piperazineethanamine Chemical Properties,Usage,Production

Uses

2-(4-Methylpiperazin-1-yl)ethanamine (cas# 934-98-5) is a useful research chemical.

Chemical Properties

Colorless liquid

Uses

1-(2-Aminoethyl)-4-methylpiperazine is used as pharmaceutical intermediate.

Definition

ChEBI: A N-alkylpiperazine that is piperazine substituted by a methyl and a 2-aminoethyl group at the N atoms respectively.

Synthesis

874-77-1

934-98-5

Step 5. To a stirred suspension of lithium aluminum hydride (3.3 g, 87 mmol) in anhydrous THF (100 mL) was slowly added a solution of 2-(4-methylpiperazin-1-yl)acetonitrile (11.2 g, 80.4 mmol) in anhydrous THF (300 mL) at 0 °C. The reaction mixture was stirred at room temperature for 1 hour. Subsequently, the mixture was cooled in an ice bath and H2O (3.3 mL) and 20% NaOH solution (3.3 mL) were added sequentially. After stirring for 20 minutes, the mixture was filtered and the solvent was evaporated. The residue was dissolved in ethyl acetate and dried with anhydrous sodium sulfate. The solvent was evaporated to dryness to give 2-(4-methylpiperazin-1-yl)ethylamine as an oil (1.15 g, 99%).1H NMR (400 MHz, CDCl3) δ: 2.21 (s, 3H), 2.20-2.60 (m, 10H), 2.71 (t, J=6.0 Hz, 2H).

References

[1] Journal of Medicinal Chemistry, 1999, vol. 42, # 15, p. 2870 - 2880
[2] Patent: WO2013/148365, 2013, A1. Location in patent: Paragraph 0086
[3] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 7, p. 2251 - 2259
[4] Patent: WO2016/16728, 2016, A2. Location in patent: Paragraph 000703; 000704
[5] Patent: WO2005/35532, 2005, A1. Location in patent: Page/Page column 30

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View Lastest Price from 4-Methyl-1-piperazineethanamine manufacturers

Shanghai Rlavie Technology Co ltd
Product
4-Methyl-1-piperazineethanamine 934-98-5
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
99%minGC
Supply Ability
1ton/month
Release date
2021-11-05
Career Henan Chemical Co
Product
4-Methyl-1-piperazineethanamine 934-98-5
Price
US $1.00/KG
Min. Order
1KG
Purity
90%-99.99%
Supply Ability
500kgs
Release date
2019-07-02

934-98-5, 4-Methyl-1-piperazineethanamineRelated Search:


  • AKOS BB-6128
  • 4-METHYL-1-PIPERAZINEETHANAMINE
  • 1-(2-AMINOETHYL)-4-METHYL-PIPERAZINE
  • 2-(4-METHYLPIPERAZIN-1-YL)ETHANAMINE
  • 2-(4-METHYL-PIPERAZIN-1-YL)-ETHYLAMINE
  • 1-(N-AMINOETHYL)-4-METHYL PIPERAZINE
  • CHEMBRDG-BB 4006383
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  • 1-(2-Aminoethyl)-4-methylpiperazine 95%
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  • 1-(2-AMINOETHYL)METHYLPIPERAZINE
  • 2-(4-Methyl-piperazin-1-yl)-ethylamine ,98%
  • 1-Methyl-4-(2-aminoethyl)piperazine
  • 2-(4-methylpiperazin-1-yl)ethanamine(SALTDATA: FREE)
  • 2-(4-Methylpiperazin-1-yl)ethylamine, 1-Amino-2-(4-methylpiperazin-1-yl)ethane
  • 1-(2-Aminoethyl)-4-methylpiperazine 98+%
  • 1-(2-AMinoethyl)-4-Methylpiperazine, 97+%
  • 1-Piperazineethanamine, 4-methyl-
  • 2-(4-methyl-1-piperazinyl)ethanamine
  • 2-(4-Methyl-1-piperazinyl)ethylamine
  • 4-Methylpiperazin-1-ethylamin
  • 1-(2-Aminoethyl)-4-methyl-piperaz
  • 934-98-5
  • C7H17N3
  • Piperaizine
  • piperazines