ChemicalBook > CAS DataBase List > AC-IETD-PNA

AC-IETD-PNA

Product Name
AC-IETD-PNA
CAS No.
219138-21-3
Chemical Name
AC-IETD-PNA
Synonyms
AX-IETD-AMC;AC-IETD-AMC;AC-IETD-MCA;AC-IETD-PNA;Z-ALA-ALA-ASP-AFC;CASPASE-8 SUBSTRATE;GRANZYME B SUBSTRATE;CASPASE-8 SUBSTRATE I;AC-ILE-GLU-THR-ASP-PNA;AC-ILE-GLU-THR-ASP-AMC
CBNumber
CB7102062
Molecular Formula
C27H38N6O12
Formula Weight
638.62
MOL File
219138-21-3.mol
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AC-IETD-PNA Property

Boiling point:
1140.8±65.0 °C(Predicted)
Density 
1.386±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO/DMF: 1 mg/mL
form 
powder
pka
4.03±0.10(Predicted)
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A4188
Product name
N-Acetyl-Ile-Glu-Thr-Asp-7-Amido-4-methylcoumarin
Purity
≥97% (HPLC), powder
Packaging
5MG
Price
$232
Updated
2025/07/31
Sigma-Aldrich
Product number
A9968
Product name
N-Acetyl-Ile-Glu-Thr-Asp-<I>p</I>-nitroanilide
Purity
&#8805;95%
Packaging
5 mg
Price
$376
Updated
2025/07/31
Sigma-Aldrich
Product number
A9968
Product name
N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide
Purity
≥95%
Packaging
5mg
Price
$430
Updated
2024/03/01
Cayman Chemical
Product number
24568
Product name
Ac-IETD-pNA
Purity
≥95%
Packaging
1mg
Price
$81
Updated
2024/03/01
Biosynth Carbosynth
Product number
FA110803
Product name
Ac-Ile-Glu-Thr-Asp-pNA
Packaging
2mg
Price
$118
Updated
2021/12/16
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AC-IETD-PNA Chemical Properties,Usage,Production

Uses

Fluorogenic substrate for caspase 8 and granzyme B.

Biological Activity

IETD is the sequence of amino acid residues 172-175 of procaspase 3, which is cleaved during apoptosis to produce the p12 subunit and a p20 peptide th at is further cleaved to form the p17 subunit of mature caspase 3.

AC-IETD-PNA Preparation Products And Raw materials

Raw materials

Preparation Products

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AC-IETD-PNA Suppliers

China 110 France 1 Germany 2 Japan 3 Switzerland 2 United Kingdom 4 United States 18 Global 140
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
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China
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Beijing Ouhe Technology Co., Ltd
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010-010-82967028 13522913783
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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China
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Chemsky（shanghai）International Co.,Ltd.
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021-50135380
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TargetMol Chemicals Inc.
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021-021-33632979 15002134094
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Shanghai Chaolan Chemical Technology Center
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Nanjing Meihao Pharmaceutical Technology Co., Ltd.
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meitaochem@126.com
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Wuxi Helen Biotechnology Co., Ltd.,
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Nanjing TGpeptide Biotechnology Co.,Ltd.
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MedBioPharmaceutical Technology Inc
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DONBOO AMINO ACID COMPANY
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Nanjing Yuanpeptide Biotech Co.，Ltd.
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Shaoxing Junyu Biotechnology Co., LTD
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Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd
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Combio (Suzhou) Ltd.
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Enzo Biochem Inc
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219138-21-3, AC-IETD-PNARelated Search:

AC-VEID-AMC GRANZYME B AFC AC-IETD-CHO AC-IETD-PNA AC-ASP-PNA

  • AC-ILE-GLU-THR-ASP-PNA
  • ACETYL-L-ISOLEUCYL-L-GLUTAMYL-L-THREONYL-L-ASPARTIC ACID ALPHA-(4-METHYLCOUMARYL-7-AMIDE)
  • Z-ALA-ALA-ASP-AFC
  • N-ACETYL-ILE-GLU-THR-ASP P-NITROANILIDE
  • N-ACETYL-ILE-GLU-THR-ASP-P-NITROANILIDE PNA
  • N-ACETYL-ILE-GLU-THR-ASP-7-AMIDO-4-METHYLCOUMARIN
  • N-ACETYL-ILE-GLU-THR-ASP-7-AMINO-4-METHYLCOUMARIN AMC
  • AC-ILE-GLU-THR-ASP-P-NITROANILIDE
  • CASPASE-3 PRECURSOR PROTEASE SUBSTRATES ;AC-ILE-GLU-THR-ASP-AMC
  • CASPASE-8 SUBSTRATE
  • Caspase-8 Chromogenic Substrate I
  • AC-IETD-PNA;AC-ILE-GLU-THR-ASP-PNA;CASPASE-8 CHROMOGENIC SUBSTRATE I
  • CASPASE 8 SUBSTRATE 1, CHROMOGENIC
  • CASPASE 8 SUBSTRATE 1M, FLUOROGENIC
  • CASPASE-8 SUBSTRATE I
  • CASPASE 8 FLUOROMETRIC SUBSTRATE
  • CASPASE-8 / CASPASE-3 PROCESSING ENZYME SUBSTRATE, FLUOROGENIC
  • CASPASE-8 / CASPASE-3 PROCESSING ENZYME SUBSTRATE (CHROMOGENIC)
  • CASPASE-3 PROCESSING SUBSTRATE II (CHROMOGENIC)
  • CASPASE-3 PROCESSING ENZYME SUBSTRATE (FLUOROGENIC)
  • CASPASE-3 PROCESSING ENZYME SUBSTRATE II (CHROMOGENIC)
  • CASPASE-6/CASPASE-8 CHROMOGENIC SUBSTRATE
  • CASPASE-6/CASPASE-8 FLUOROGENIC SUBSTRATE
  • GRANZYME B SUBSTRATE
  • GRANZYME B SUBSTRATE 2 (CHROMOGENIC)
  • GRANZYME B SUBSTRATE (CHROMOGENIC)
  • GRANZYME B SUBSTRATE (FLUOROGENIC)
  • GRANZYME B SUBSTRATE I, COLORIMETRIC
  • GRANZYME B SUBSTRATE II (CHROMOGENIC)
  • FLUOROGENIC CASPASE 8 SUBSTRATE AC-IETD-AMC
  • AX-IETD-AMC
  • AC-IETD-AMC
  • AC-IETD-MCA
  • AC-IETD-PNA
  • AC-ILE-GLU-THR-ASP-7-AMINO-4-METHYLCOUMARIN
  • AC-ILE-GLU-THR-ASP-AMC
  • AC-ILE-GLU-THR-ASP-MCA
  • AC-ILE-GLU-THR-ASP-PARANITROANILIDE
  • L-α-Asparagine, N-acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-(4-nitrophenyl)-
  • Caspase 8 Substrate 1, chromogenic - 5 mg
  • (4S,7S,10S,13S)-4-((S)-sec-Butyl)-7-(2-carboxyethyl)-10-((R)-1-hydroxyethyl)-13-((4-nitrophenyl)carbamoyl)-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid
  • 219138-21-3
  • C31H41N5O12
  • C27H38N6O12
  • Peptide
  • Pepetides