Carbodine

Product Name: Carbodine
CAS No.: 71184-20-8
Chemical Name: Carbodine
Synonyms: C-Cyd;Carbodine;Carbodine (Carbocyclic cytidine);4-Amino-1-[(1R)-2α,3α-dihydroxy-4β-(hydroxymethyl)cyclopentan-1β-yl]-2(1H)-pyrimidinone;4-Amino-1-[(1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]-2(1H)-pyrimidinone;2(1H)-Pyrimidinone, 4-amino-1-[(1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]-
CBNumber: CB71178217
Molecular Formula: C10H15N3O4
Formula Weight: 241.24
MOL File: 71184-20-8.mol

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Carbodine Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO

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Hazard and Precautionary Statements (GHS)

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Carbodine Chemical Properties,Usage,Production

Uses

Carbodine (Carbocyclic cytidine) is a broad-spectrum antiviral agent active against DNA viruses, (+)RNA viruses, (-)RNA viruses, paramyxo, rhabdo and (+/-)RNA viruses, targets CTP synthetase that converts UTP to CTP. Carbodine (Carbocyclic cytidine) possesses significant antiviral activity against influenza virus types A0/PR-8/34 and A2/Aichi/2/68 in vitro[1][2].

References

[1] De Clercq E, et al. Broad-spectrum antiviral activity of carbodine, the carbocyclic analogue of cytidine. Biochem Pharmacol. 1990 Jan 15;39(2):319-25. DOI:10.1016/0006-2952(90)90031-f
[2] Shannon WM, et al. Evaluation of carbodine, the carbocyclic analog of cytidine, and related carbocyclic analogs of pyrimidine nucleosides for antiviral activity against human influenza Type A viruses. Antimicrob Agents Chemother. 1981 Dec;20(6):769-76. DOI:10.1128/AAC.20.6.769

Carbodine Preparation Products And Raw materials

Raw materials

Preparation Products

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Carbodine Suppliers

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71184-20-8, CarbodineRelated Search:

Carbodine

4-Amino-1-[(1R)-2α,3α-dihydroxy-4β-(hydroxymethyl)cyclopentan-1β-yl]-2(1H)-pyrimidinone

C-Cyd

Carbodine (Carbocyclic cytidine)

2(1H)-Pyrimidinone, 4-amino-1-[(1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]-

4-Amino-1-[(1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]-2(1H)-pyrimidinone

71184-20-8