girinimbine

Product Name: girinimbine
CAS No.: 23095-44-5
Chemical Name: girinimbine
Synonyms: Girinimbin;girinimbine;Girinimbine, 10 mM in DMSO;3,3,5-Trimethyl-3,11-dihydropyrano[3,2-a]carbazole;3,11-Dihydro-3,3,5-trimethylpyrano[3,2-a]carbazole;Pyrano[3,2-a]carbazole, 3,11-dihydro-3,3,5-trimethyl-
CBNumber: CB71354004
Molecular Formula: C18H17NO
Formula Weight: 263.33
MOL File: 23095-44-5.mol

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girinimbine Property

Melting point:: 176 °C
Boiling point:: 450.0±34.0 °C(Predicted)
Density: 1.187±0.06 g/cm3(Predicted)
pka: 17.31±0.40(Predicted)
form: Solid
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

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girinimbine Chemical Properties,Usage,Production

Uses

Girinimbine is a carbazole alkaloid with a variety of biological effects. Girinimbine can induce apoptosis and has antibacterial, anti-inflammatory, antioxidant and antitumor activities.

Definition

ChEBI: A natural product found in Clausena harmandiana.

in vivo

Girinimbine (10-100 mg/kg; orally gavage; once) pretreatment helps limit total leukocyte migration, and reduced pro-inflammatory cytokine (IL-1β, TNF-α) levels in the peritoneal fluid^[2].
In vivo in zebrafish embryos, Girinimbine (20 μg/mL; 24 hours) shows significant distribution of apoptotic cells in embryos^[2].

Animal Model:	Male ICR mice (25-35 g) treated with carrageenan^[2]
Dosage:	10 mg/kg, 30 mg/kg, and 100 mg/kg
Administration:	Orally gavage; once
Result:	Helped limit total leukocyte migration, and reduced pro-inflammatory cytokine levels in the peritoneal fluid.

girinimbine Preparation Products And Raw materials

Raw materials

Preparation Products

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girinimbine Suppliers

China 27 South Korea 1 The Netherlands 1 United States 4 Global 33

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23095-44-5, girinimbineRelated Search:

girinimbine

3,11-Dihydro-3,3,5-trimethylpyrano[3,2-a]carbazole

Pyrano[3,2-a]carbazole, 3,11-dihydro-3,3,5-trimethyl-

Girinimbin

Girinimbine, 10 mM in DMSO

3,3,5-Trimethyl-3,11-dihydropyrano[3,2-a]carbazole

23095-44-5