ChemicalBook > CAS DataBase List > girinimbine
girinimbine
- Product Name
- girinimbine
- CAS No.
- 23095-44-5
- Chemical Name
- girinimbine
- Synonyms
- Girinimbin;girinimbine;Girinimbine, 10 mM in DMSO;3,3,5-Trimethyl-3,11-dihydropyrano[3,2-a]carbazole;3,11-Dihydro-3,3,5-trimethylpyrano[3,2-a]carbazole;Pyrano[3,2-a]carbazole, 3,11-dihydro-3,3,5-trimethyl-
- CBNumber
- CB71354004
- Molecular Formula
- C18H17NO
- Formula Weight
- 263.33
- MOL File
- 23095-44-5.mol
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girinimbine Property
- Melting point:
- 176 °C
- Boiling point:
- 450.0±34.0 °C(Predicted)
- Density
- 1.187±0.06 g/cm3(Predicted)
- pka
- 17.31±0.40(Predicted)
- form
- Solid
- color
- Off-white to light yellow
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girinimbine Chemical Properties,Usage,Production
Uses
Girinimbine is a carbazole alkaloid with a variety of biological effects. Girinimbine can induce apoptosis and has antibacterial, anti-inflammatory, antioxidant and antitumor activities.
Definition
ChEBI: A natural product found in Clausena harmandiana.
in vivo
Girinimbine (10-100 mg/kg; orally gavage; once) pretreatment helps limit total leukocyte migration, and reduced pro-inflammatory cytokine (IL-1β, TNF-α) levels in the peritoneal fluid[2].
In vivo in zebrafish embryos, Girinimbine (20 μg/mL; 24 hours) shows significant distribution of apoptotic cells in embryos[2].
| Animal Model: | Male ICR mice (25-35 g) treated with carrageenan[2] |
| Dosage: | 10 mg/kg, 30 mg/kg, and 100 mg/kg |
| Administration: | Orally gavage; once |
| Result: | Helped limit total leukocyte migration, and reduced pro-inflammatory cytokine levels in the peritoneal fluid. |
girinimbine Preparation Products And Raw materials
Raw materials
Preparation Products
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girinimbine Suppliers
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- Fax
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- sales21@chemicalland21.com
- Country
- South Korea
- ProdList
- 6303
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