ChemicalBook > CAS DataBase List > REMOXIPRIDE HYDROCHLORIDE

REMOXIPRIDE HYDROCHLORIDE

Product Name
REMOXIPRIDE HYDROCHLORIDE
CAS No.
73220-03-8
Chemical Name
REMOXIPRIDE HYDROCHLORIDE
Synonyms
CV236900;(s)-(-)-d;(-)-fla732;REMOXIPRIDE HYDROCHLORIDE;(S)-ReMoxipride Hydrochloride;Remoxipride Hydrochloride (anhydrous);3-bromo-2,6-dimethoxy-n-(1-ethyl-2-pyrrolidinylmethyl)-benzamidhydrochlori;S-(-)-3-BROMO-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2,6-DIMETHOXYBENZAMIDE HCL;(s)-(-)-3-bromo-2,6-dimethoxy-n-(1-ethyl-2-pyrrolidinylmethyl)benzamidehydro;(s)-(-)-2-((3-bromo-2,6-dimethoxybenzamido)methyl)-1-ethylpyrrolidinehydroch
CBNumber
CB7215621
Molecular Formula
C16H24BrClN2O3
Formula Weight
407.73
MOL File
73220-03-8.mol
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REMOXIPRIDE HYDROCHLORIDE Property

Melting point:
168-169 °C
storage temp. 
Store at RT
solubility 
Chloroform (Sparingly), Water (Slightly, Sonicated)
form 
White solid.
color 
White to Off-White
Water Solubility 
Soluble to 100 mM in water
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
0916
Product name
Remoxipridehydrochloride
Packaging
10
Price
$159
Updated
2021/12/16
Tocris
Product number
0916
Product name
Remoxipridehydrochloride
Packaging
50
Price
$647
Updated
2021/12/16
Usbiological
Product number
256438
Product name
Remoxipride hydrochloride
Packaging
10mg
Price
$403
Updated
2021/12/16
TRC
Product number
R143700
Product name
(S)-RemoxiprideHydrochloride
Packaging
100mg
Price
$1135
Updated
2021/12/16
ApexBio Technology
Product number
B6501
Product name
Remoxipridehydrochloride
Packaging
10mg
Price
$234
Updated
2021/12/16
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REMOXIPRIDE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Specific dopamine D2-receptor antagonist. Antipsychotic.

Biological Activity

Standard D 2 receptor antagonist showing some selectivity over D 3 and D 4 receptors (K i values are ~ 300, ~ 1600, and ~ 2800 nM for D 2 , D 3 and D 4 receptors respectively). In vivo remoxipride is an antipsychotic which does not cause extrapyramidal side effects and is 50-fold more potent than sulpiride in antagonising the effects of apomorphine in the rat.

in vivo

(S)-Remoxipride hydrochloride (0.1-100 μM/kg; i.p. 60 min prior to apomorphine) blockades apomorphine-induced behaviors s in rats and vomiting in dogs[1]. (S)-Remoxipride hydrochloride (0.1-10 mg/kg; i.p. 30 min prior to apomorphine) displaces [3H]spiperone from both striatal and extra-striatal areas[1].

REMOXIPRIDE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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REMOXIPRIDE HYDROCHLORIDE Suppliers

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73220-03-8, REMOXIPRIDE HYDROCHLORIDERelated Search:


  • (-)-fla732
  • (s)-(-)-2-((3-bromo-2,6-dimethoxybenzamido)methyl)-1-ethylpyrrolidinehydroch
  • (s)-(-)-3-bromo-2,6-dimethoxy-n-(1-ethyl-2-pyrrolidinylmethyl)benzamidehydro
  • (s)-(-)-d
  • 3-bromo-2,6-dimethoxy-n-(1-ethyl-2-pyrrolidinylmethyl)-benzamidhydrochlori
  • S-(-)-3-BROMO-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2,6-DIMETHOXYBENZAMIDE HCL
  • (S)-(-)-3-BROMO-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]2,6-DIMETHOXYBENZAMIDE HYDROCHLORIDE
  • REMOXIPRIDE HYDROCHLORIDE
  • (S)-ReMoxipride Hydrochloride
  • (-)-(S)-3-Brom-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2,6-dimethoxybenzamide hydrochloride
  • CV236900
  • (S)-(-)-3-BROMO-N-[(1-ETHYL-2-PYRROLIDINYL0METHYL]2,6-DIMETHOXYBENZAMIDE HYDROCHLORIDE
  • Remoxipride Hydrochloride (anhydrous)
  • 73220-03-8
  • C16H24BrClN2O3
  • C16H23BrN2O3HCl
  • C16H23BrN2O3HClH2O
  • Dopamine receptor
  • Aromatics
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals