1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE
- Product Name
- 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE
- CAS No.
- 100991-92-2
- Chemical Name
- 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE
- Synonyms
- 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE;2-Hydroxymethyl-3,4-pyrrolidinediol hydrochloride;1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride enzyme inhibitor;3,4-Pyrrolidinediol, 2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R)-;(2R,3R,4R)-3,4-Dihydroxy-2-(hydroxymethyl)pyrrolidine hydrochloride
- CBNumber
- CB7230309
- Molecular Formula
- C5H12ClNO3
- Formula Weight
- 169.61
- MOL File
- Mol file
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1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Property
- Melting point:
- 110-112 °C(Solv: ethyl ether (60-29-7); methanol (67-56-1))
- storage temp.
- 2-8°C
- solubility
- DMSO: 10 mg/ml; PBS (pH 7.2): 1 mg/ml
- form
- A crystalline solid
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- D1542
- Product name
- 1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride
- Purity
- enzyme inhibitor
- Packaging
- 10mg
- Price
- $762
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- D1542
- Product name
- 1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride
- Purity
- enzyme inhibitor
- Packaging
- 25mg
- Price
- $1700
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 20939
- Product name
- 1,4-dideoxy-1,4-imino-D-Arabinitol (hydrochloride)
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $38
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 20939
- Product name
- 1,4-dideoxy-1,4-imino-D-Arabinitol (hydrochloride)
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $166
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 20939
- Product name
- 1,4-dideoxy-1,4-imino-D-Arabinitol (hydrochloride)
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $292
- Updated
- 2024/03/01
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1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Chemical Properties,Usage,Production
Description
1,4-dideoxy-1,4-imino-D-Arabinitol (DAB) is an inhibitor of glycogen phosphorylase, a key enzyme in glycogenolysis. It inhibits glycogenolysis in isolated liver cells (IC50 = 1.0 μM) and in homogenates of cerebral cortex and cerebellum (IC50s = 463 and 383 nM, respectively). DAB is used to inhibit glycogenolysis, in liver and in brain, in various animal models.
Uses
1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride has been used as an α-glucosidase (GAA) inhibitor.
General Description
1,4-Dideoxy-1,4-imino-D-arabinitol is a naturally occurring pyrrolidine alkaloid. It is found in Arachniodes standishii and Angylocalyx boutiqueanus.
Biochem/physiol Actions
Inhibitor of glycogen phosphorylase and α-glucosidases.
1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Suppliers
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