5-AMINO-3-BROMOBENZONITRILE

Product Name: 5-AMINO-3-BROMOBENZONITRILE
CAS No.: 49674-16-0
Chemical Name: 5-AMINO-3-BROMOBENZONITRILE
Synonyms: 3-Bromo-5-cyanoaniline;3-Amino-5-bromobenzonitrile;5-AMINO-3-BROMOBENZONITRILE;Benzonitrile, 3-amino-5-bromo-
CBNumber: CB72455984
Molecular Formula: C7H5BrN2
Formula Weight: 197.03
MOL File: 49674-16-0.mol

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5-AMINO-3-BROMOBENZONITRILE Property

Boiling point:: 320.2±22.0 °C(Predicted)
Density: 1.68±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 1.72±0.10(Predicted)
form: powder
color: Off-white

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Safety

HS Code: 2926907090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC

Product number: A594155
Product name: 3-Amino-5-bromobenzonitrile
Packaging: 100mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 072870
Product name: 5-Amino-3-bromobenzonitrile
Purity: 95+%
Packaging: 1g
Price: $59
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA64099
Product name: 3-Amino-5-bromobenzonitrile
Packaging: 500g
Price: $80
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA64099
Product name: 3-Amino-5-bromobenzonitrile
Packaging: 1g
Price: $125
Updated: 2021/12/16

Matrix Scientific

Product number: 072870
Product name: 5-Amino-3-bromobenzonitrile
Purity: 95+%
Packaging: 5g
Price: $179
Updated: 2021/12/16

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5-AMINO-3-BROMOBENZONITRILE Chemical Properties,Usage,Production

Synthesis

49674-15-9

49674-16-0

General procedure for the synthesis of 5-amino-3-bromobenzonitrile from 3-bromo-5-nitrobenzonitrile: 3-bromo-5-nitrobenzonitrile (3 g, 13.2 mmol) was dissolved in methanol (100 mL) and cooled in an ice water bath. To this solution zinc powder (3.46 g, 52.9 mmol) and acetic acid (6.05 mL, 106 mmol) were added sequentially. Exothermic phenomenon was observed 1 minute after the start of the reaction. After the reaction was carried out for 2 hours, the reaction mixture was filtered through diatomaceous earth and the filtrate was concentrated to give the crude product. The crude product was purified using silica gel chromatography with a hexane solution of 0 to 50% ethyl acetate as eluent. The eluate containing the target product was collected and concentrated by evaporation to give 5-amino-3-bromobenzonitrile (2.1 g, 81% yield). The product was analyzed by high performance liquid chromatography (HPLC): retention time (RT) = 0.80 min (Waters Acquity UPLC BEH C18 column, 1.7 μm, 2.0 × 50 mm, mobile phase acetonitrile/water/0.05% trifluoroacetic acid, gradient elution, detection wavelength = 254 nm); mass spectrum (ES): m/z = 196.9/ 198.9 (79Br/81Br)[M+H]+; 1H NMR (DMSO-d6) δ 7.06-7.09 (m, 1H), 7.04 (t, J=2.0Hz, 1H), 6.87 (dd, J=2.1,1.4Hz, 1H), 5.91 (s, 2H).

References

[1] Patent: WO2016/183114, 2016, A1. Location in patent: Page/Page column 61
[2] Patent: WO2009/42694, 2009, A1. Location in patent: Page/Page column 111
[3] Patent: WO2009/42694, 2009, A1. Location in patent: Page/Page column 71
[4] Patent: WO2012/93101, 2012, A1. Location in patent: Page/Page column 241-242

5-AMINO-3-BROMOBENZONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-AMINO-3-BROMOBENZONITRILE Suppliers

China 95 Germany 1 India 5 United Kingdom 2 United States 6 Global 109

Energy Chemical

Tel: 021-021-58432009 400-005-6266
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Shanghai Hanhong Scientific Co.,Ltd.

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Beijing Eternalchem Co,. Ltd.

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Shanghai Sphchem Co., Ltd.

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NovoChemy Ltd.

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Shanghai Topbiochem Technology Co., Ltd

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9ding chemical ( Shanghai) Limited

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View Lastest Price from 5-AMINO-3-BROMOBENZONITRILE manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: 5-Amino-3-bromobenzonitrile 49674-16-0
Price: US $5.10/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10kg
Release date: 2021-09-24

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: 5-Amino-3-bromobenzonitrile 49674-16-0
Price: US $5.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 10KG
Release date: 2021-11-26

Career Henan Chemical Co

Product: 5-AMINO-3-BROMOBENZONITRILE 49674-16-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-25

49674-16-0, 5-AMINO-3-BROMOBENZONITRILERelated Search:

1-Amino-2-bromonaphthalene 3-Amino-5-bromobenzotrifluoride 2-AMINO-4-BROMO-6-CYANOTOLUENE 5-BROMO-2-HYDROXY-3-NITROBENZONITRILE 5-AMINO-3-BROMOBENZONITRILE Disperse Blue 183 3-BROMO-6-METHYL-5-NITROBENZENENITRILE 3-BROMO-2,6-DIHYDROXY-5-NITROBENZONITRILE 3-Bromo-5-nitrobenzonitrile 2-Amino-3-bromo-5-nitrobenzonitrile

5-AMINO-3-BROMOBENZONITRILE

3-Amino-5-bromobenzonitrile

3-Bromo-5-cyanoaniline

Benzonitrile, 3-amino-5-bromo-

49674-16-0