ChemicalBook > CAS DataBase List > CA1P
CA1P
- Product Name
- CA1P
- CAS No.
- 288847-34-7
- Chemical Name
- CA1P
- Synonyms
- CA1P;OXi-4503 sodium;Tetrasodium A1 Diphosphate;COMBRETASTATIN A-1 PHOSPHATE;TetrasodiuM coMbretastatin A1 diphosphate;Oxi 4503 Combretastatin A-1 phosphate , CA1P;CoMbretastatin A1 diphosphate tetrasodiuM salt;tetrasodium,[3-methoxy-2-phosphonooxy-6-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] dihydrogen phosphate;3-Methoxy-6-[(Z)-2-(3,4,5-trimethoxyphenyl)vinyl]-1,2-benzenediol bis(dihydrogen phosphate) tetrasodium salt
- CBNumber
- CB72522392
- Molecular Formula
- C18H23NaO12P2
- Formula Weight
- 516.31
- MOL File
- 288847-34-7.mol
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0026173
- Product name
- 3-METHOXY-6-[(Z)-2-(3,4,5-TRIMETHOXYPHENYL)VINYL]-1,2-BENZENEDIOL BIS(DIHYDROGEN PHOSPHATE)TETRASODIUM
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $1904.79
- Updated
- 2021/12/16
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CA1P Chemical Properties,Usage,Production
Description
OXi-4503 is the diphosphate prodrug of the stilbenoid combretastatin A1, originally isolated from the plant Combretum caffrum, with vascular-disrupting and antineoplastic activities. Upon administration, combretastatin A1 diphosphate (CA1P) is dephosphorylated to the active metabolite combretastatin A1 (CA1), which promotes rapid microtubule depolymerization; endothelial cell mitotic arrest and apoptosis, destruction of the tumor vasculature, disruption of tumor blood flow and tumor cell necrosis may ensue.
CA1P Preparation Products And Raw materials
Raw materials
Preparation Products
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CA1P Suppliers
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