ChemicalBook > CAS DataBase List > 3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride

3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride

Product Name
3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride
CAS No.
849727-62-4
Chemical Name
3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride
Synonyms
Paliperidone Impurity 1 HCl;Paliperidone Impurity 11 Hydrochloride;Paliperidone Tetradehydro Chloroethyl Impurity;3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidine-4-one;3-(2-Chloroethyl)-9-Hydroxy-2-Methyl-4H-Pyrido[1,2-a] Pyrimidin-4-One HCl;3-(2-Chloroethyl)-9-Hydroxy-2-Methyl-4H-Pyrido[1,2-a] Pyrimidin-4-One HCI;3-(2-chloroethyl)-9-hydroxy-2-methylpyrido[1,2-a]pyrimidin-4-one,hydrochloride;3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride
CBNumber
CB72534142
Molecular Formula
C11H12Cl2N2O2
Formula Weight
275.13118
MOL File
849727-62-4.mol
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3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride Property

Melting point:
>218°C (dec.)
Density 
1.6g/cm3 at 20℃
vapor pressure 
0-0Pa at 20-25℃
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
Yellow to Dark Yellow
LogP
1.9 at 20℃ and pH7
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H341Suspected of causing genetic defects

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
C364240
Product name
3-(2-Chloroethyl)-9-hydroxy-2-methyl-4H-Pyrido[1,2-a]pyrimidin-4-oneHydrochloride
Packaging
25mg
Price
$215
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
68592
Product name
3-(2-Chloroethyl)-9-hydroxy-2-methyl-4H-Pyrido[1,2-α]pyrimidin-4-oneHCl
Packaging
25mg
Price
$675
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
68592
Product name
3-(2-Chloroethyl)-9-hydroxy-2-methyl-4H-Pyrido[1,2-α]pyrimidin-4-oneHCl
Packaging
250mg
Price
$2400
Updated
2021/12/16
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3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride Chemical Properties,Usage,Production

Uses

3-(2-Chloroethyl)-9-hydroxy-2-methyl-4H-Pyrido[1,2-a]pyrimidin-4-one Hydrochloride is an intermediate in the synthesis of analog of Paliperidone (P141000), a combined serotonin and dopamine receptor antagonist.

3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride Suppliers

Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71

849727-62-4, 3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochlorideRelated Search:


  • 3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride
  • Paliperidone Tetradehydro Chloroethyl Impurity
  • 3-(2-Chloroethyl)-9-Hydroxy-2-Methyl-4H-Pyrido[1,2-a] Pyrimidin-4-One HCl
  • 3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidine-4-one
  • Paliperidone Impurity 1 HCl
  • 3-(2-Chloroethyl)-9-Hydroxy-2-Methyl-4H-Pyrido[1,2-a] Pyrimidin-4-One HCI
  • 3-(2-chloroethyl)-9-hydroxy-2-methylpyrido[1,2-a]pyrimidin-4-one,hydrochloride
  • Paliperidone Impurity 11 Hydrochloride
  • 849727-62-4
  • 849729-62-4