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JWH 200-d5

Product Name
JWH 200-d5
CAS No.
1651833-51-0
Chemical Name
JWH 200-d5
Synonyms
JWH 200-d5;JWH 200-d5 (exempt preparation)
CBNumber
CB72591497
Molecular Formula
C25H24N2O2
Formula Weight
384.48
MOL File
1651833-51-0.mol
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JWH 200-d5 Property

solubility 
Acetonitrile: 14 mg/ml; DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:6): 0.1 mg/ml; DMSO: 20 mg/ml; Methanol: 2 mg/ml; Methyl Acetate: 5 mg/ml
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10682
Product name
JWH 200-d5 (exempt preparation)
Purity
≥99% deuterated forms (d1-d5)
Packaging
500μg
Price
$79
Updated
2024/03/01
Cayman Chemical
Product number
10682
Product name
JWH 200-d5 (exempt preparation)
Purity
≥99% deuterated forms (d1-d5)
Packaging
1mg
Price
$150
Updated
2024/03/01
Cayman Chemical
Product number
10903
Product name
JWH 200-d5
Purity
≥99% deuterated forms (d1-d5)
Packaging
500μg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
10903
Product name
JWH 200-d5
Purity
≥99% deuterated forms (d1-d5)
Packaging
1mg
Price
$152
Updated
2024/03/01
Cayman Chemical
Product number
10682
Product name
JWH 200-d5 (exempt preparation)
Purity
≥99% deuterated forms (d1-d5)
Packaging
5mg
Price
$594
Updated
2024/03/01
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JWH 200-d5 Chemical Properties,Usage,Production

Description

JWH 200-d5 contains five deuterium atoms at the 2', 4' ,5', 6', and 7' positions. It is intended for use as an internal standard for the quantification of JWH 200 by GC- or LC-mass spectrometry. JWH 200 is an aminoalkylindole that acts as a cannabinoid (CB) receptor ligand. It binds to the CB1 receptor with high-affinity (IC50 = 7.8-42 nM).1,2 The effects of JWH 200 in locomotor activity, tail-flick latency, hypothermia, and ring-immobility tests are comparable or superior to Δ9-THC or WIN 55,212.3 It potently inhibits the contraction of electrically-stimulated mouse vas deferens (IC50 = 3.7-6.0 nM).4,5

References

1. Eissenstat, M.A., Bell, M.R., D'Ambra, T.E., et al. Aminoalkylindoles: Structure-activity relationships of novel cannabinoid mimetics J. Med. Chem. 38,3094-3105(1995).
2. Huffman, J.W., Mabon, R., Wu, M.J., et al. 3-indolyl-1-naphthylmethanes: New cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor Bioorgan. Med. Chem. 11(4),539-549(2003).
3. Compton, D.R., Gold, L.H., Ward, S.J., et al. Aminoalkylindole analogs: Cannabimimetic activity of a class of compounds structurally distinct from D 9-tetrahydrocannabinol J. Pharmacol. Exp. Ther. 263(3),1118-1126(1992).
4. Pacheco, M., Childers, S.R., Arnold, R., et al. Aminoalkylindoles: Actions on specific G-protein-linked receptors J. Pharmacol. Exp. Ther. 257(1),170-183(1991).
5. Bell, M.R., D'Ambra, T.E., Kumar, V., et al. Antinociceptive (aminoalkyl) indoles J. Med. Chem. 34,1099-1110(1991).

JWH 200-d5 Preparation Products And Raw materials

Raw materials

Preparation Products

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JWH 200-d5 Suppliers

Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
Absin Bioscience Inc.
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6705
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58
Shanghai Haoran Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
470003480@QQ.COM
Country
CHINA
ProdList
6955
Advantage
58
Resenbio
Tel
--
Fax
--
Email
sales@xarxbio.com
Country
China
ProdList
1774
Advantage
50
Beijing Bolide Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1985563437@qq.com
Country
CHINA
ProdList
6158
Advantage
58
Shenzhen Xinbosheng Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
service@neobioscience.com
Country
CHINA
ProdList
6151
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
market@xlswkj.com
Country
CHINA
ProdList
6793
Advantage
58
Beijing Fubo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
info@f-biology.com
Country
CHINA
ProdList
6025
Advantage
58
Shanghai Jijin Chemical Technology Co., Ltd.
Tel
--
Fax
--
Email
jijinhuaxue@sina.com
Country
CHINA
ProdList
6606
Advantage
58

1651833-51-0, JWH 200-d5Related Search:


  • JWH 200-d5
  • JWH 200-d5 (exempt preparation)
  • 1651833-51-0