2-CHLORO-2,2-DIFLUOROACETOPHENONE
- Product Name
- 2-CHLORO-2,2-DIFLUOROACETOPHENONE
- CAS No.
- 384-67-8
- Chemical Name
- 2-CHLORO-2,2-DIFLUOROACETOPHENONE
- Synonyms
- 2-Chloro-2,2-difluoro-1-phenylethan-1-one;Ethanone, 2-chloro-2,2-difluoro-1-phenyl-;2-Chloro-2,2-d;CHLORODIFLUOROACETOPHENONE;à,à-difluorophenacyl chloride;à-chloro-à,à-difluoroacetophene;A-CHLORO-A,A-DIFLUOROACETOPHENONE;2-CHLORO-2,2-DIFLUOROACETOPHENONE;α,α-Difluoro-α-chloroacetophenone;ChlorodifluoroMethyl phenyl ketone
- CBNumber
- CB7297366
- Molecular Formula
- C8H5ClF2O
- Formula Weight
- 190.57
- MOL File
- 384-67-8.mol
2-CHLORO-2,2-DIFLUOROACETOPHENONE Property
- Melting point:
- 102-103 °C
- Boiling point:
- 94-96 °C35 mm Hg(lit.)
- Density
- 1.293 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.497(lit.)
- Flash point:
- 163 °F
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Difficult to mix.
- form
- liquid
- color
- Clear, colourless
- BRN
- 2251448
- CAS DataBase Reference
- 384-67-8(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 792373
- Product name
- 2-Chloro-2,2-difluoroacetophenone
- Purity
- 95%
- Packaging
- 10g
- Price
- $179.4
- Updated
- 2024/03/01
- Product number
- 792373
- Product name
- 2-Chloro-2,2-difluoroacetophenone
- Purity
- 95%
- Packaging
- 1g
- Price
- $63.2
- Updated
- 2023/06/20
- Product number
- L16963
- Product name
- 2-Chloro-2,2-difluoroacetophenone, 96%
- Packaging
- 1g
- Price
- $96.65
- Updated
- 2024/03/01
- Product number
- L16963
- Product name
- 2-Chloro-2,2-difluoroacetophenone, 96%
- Packaging
- 5g
- Price
- $377.65
- Updated
- 2024/03/01
- Product number
- C423215
- Product name
- 2-Chloro-2,2-difluoroacetophenone
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
2-CHLORO-2,2-DIFLUOROACETOPHENONE Chemical Properties,Usage,Production
Description
Novel and non-ODS-based (ODS = ozone-depleting substance) difluorocarbene reagents for O- and N-difluoromethylation. PhCOCF2Cl reacts with a variety of structurally diverse phenol derivatives to produce aryl difluoromethyl ethers in good yields. PhSO2CF2Cl can react with a variety of structurally diverse phenol derivatives and N-heterocyclic compounds.
Uses
2-Chloro-2,2-difluoroacetophenone can be used:
- As a reagent in the difluoromethylation of various phenols to yield aryl difluoromethyl ethers.
- As a precursor in the Baylis-Hillman reaction of fluoroalkyl ketones to obtain chlorodifluoromethyl containing products.
- As a substrate in the synthesis of propargyl alcohols using a novel ruthenium catalyst.
General Description
2-Chloro-2,2-difluoroacetophenone is a difluorocarbene reagent, which is generally used in the synthesis of 2,2-difluoro enol silyl ethers, and gem?-difluoromethene derived compounds.
2-CHLORO-2,2-DIFLUOROACETOPHENONE Preparation Products And Raw materials
Raw materials
Preparation Products
2-CHLORO-2,2-DIFLUOROACETOPHENONE Suppliers
View Lastest Price from 2-CHLORO-2,2-DIFLUOROACETOPHENONE manufacturers
- Product
- 2-Chloro-2,2-difluoroacetophenone 384-67-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.8%
- Supply Ability
- 100 tons
- Release date
- 2022-02-21