ChemicalBook > CAS DataBase List > TC-I 15

TC-I 15

Product Name
TC-I 15
CAS No.
916734-43-5
Chemical Name
TC-I 15
Synonyms
TC-I 15;TCI 15,TC I 15;XKLHCUGVLCGKKX-RBUKOAKNSA-N;N-[[(4R)-5,5-Dimethyl-3-(phenylsulfonyl)-4-thiazolidinyl]carbonyl]-3-[[[(phenylmethyl)amino]carbonyl]amino]-L-alanine;L-Alanine, N-[[(4R)-5,5-dimethyl-3-(phenylsulfonyl)-4-thiazolidinyl]carbonyl]-3-[[[(phenylmethyl)amino]carbonyl]amino]-
CBNumber
CB73037552
Molecular Formula
C23H28N4O6S2
Formula Weight
520.62
MOL File
916734-43-5.mol
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TC-I 15 Property

storage temp. 
Store at -20°C
solubility 
Soluble to 100 mM in DMSO and to 25 mM in 1.1eq. NaOH
form 
Powder
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
4527
Product name
TC-I15
Purity
≥98%(HPLC)
Packaging
10
Price
$266
Updated
2021/12/16
Tocris
Product number
4527
Product name
TC-I15
Purity
≥98%(HPLC)
Packaging
50
Price
$1060
Updated
2021/12/16
TRC
Product number
T012100
Product name
TC-I15
Packaging
50mg
Price
$845
Updated
2021/12/16
TRC
Product number
T012100
Product name
TC-I15
Packaging
100mg
Price
$1485
Updated
2021/12/16
ApexBio Technology
Product number
B5631
Product name
TC-I15
Packaging
10mg
Price
$385
Updated
2021/12/16
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TC-I 15 Chemical Properties,Usage,Production

Uses

TC-I 15 is an inhibitor of integrin α2β1, a collagen receptor. TC-I 15 has shown to prevent pathological thrombus formation .

in vivo

TC I-15 (10 μg; intravenous injection; every other day; for three weeks) inhibits lung metastasis promoted by CAFs EVs in mice[2].

Animal Model:C57BL/6 J mice[2]
Dosage:10 μg; every other day for 3 weeks; once every 2 weeks for 3 weeks
Administration:Intravenous injection (i.v.)
Result:Inhibited the formation of pre-metastatic microenvironment induced by EVs, inhibited SACC lung metastasis induced by EVs, and significantly increased integrin β1 of EVs.

IC 50

α2β1: 0.4 (α2β1 μM (IC50); α2β1: 26.8 (α2β1 μM (IC50); α1β1: 23.6 (α1β1 μM (IC50); α1β1: 24.4 (α1β1 μM (IC50); α11β1: 177 (α11β1 μM (IC50); α11β1: 3177 (α11β μM (IC50)

storage

Store at -20°C

TC-I 15 Preparation Products And Raw materials

Raw materials

Preparation Products

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TC-I 15 Suppliers

CHINA 23 United Kingdom 1 United States 5 Global 29
Career Henan Chemica Co
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916734-43-5, TC-I 15Related Search:


  • TC-I 15
  • XKLHCUGVLCGKKX-RBUKOAKNSA-N
  • N-[[(4R)-5,5-Dimethyl-3-(phenylsulfonyl)-4-thiazolidinyl]carbonyl]-3-[[[(phenylmethyl)amino]carbonyl]amino]-L-alanine
  • L-Alanine, N-[[(4R)-5,5-dimethyl-3-(phenylsulfonyl)-4-thiazolidinyl]carbonyl]-3-[[[(phenylmethyl)amino]carbonyl]amino]-
  • TCI 15,TC I 15
  • 916734-43-5
  • C23H28N4O6S2