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trabodenoson

Product Name
trabodenoson
CAS No.
871108-05-3
Chemical Name
trabodenoson
Synonyms
PJ 875;INO-8875;INNO-8875;trabodenoson;Trabodenoson, 10 mM in DMSO;N-Cyclopentyladenosine 5'-nitrate;Adenosine, N-cyclopentyl-, 5'-nitrate;((2R,3S,4R,5R)-5-(6-(CYCLOPENTYLAMINO)-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHYL NITRATE
CBNumber
CB73067203
Molecular Formula
C15H20N6O6
Formula Weight
380.36
MOL File
871108-05-3.mol
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trabodenoson Property

Boiling point:
691.2±65.0 °C(Predicted)
Density 
1.87±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO: soluble
form 
A crystalline solid
pka
12.99±0.70(Predicted)
color 
White to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0024616
Product name
Trabodenoson
Purity
98.14%
Packaging
5mg
Price
$400
Updated
2021/12/16
Crysdot
Product number
CD70000284
Product name
Trabodenoson
Purity
97%
Packaging
50mg
Price
$430
Updated
2021/12/16
Crysdot
Product number
CD70000284
Product name
Trabodenoson
Purity
97%
Packaging
250mg
Price
$1292
Updated
2021/12/16
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trabodenoson Chemical Properties,Usage,Production

Uses

Trabodenoson alters ECM turnover by TM cells and increases conventional outflow facility, which accounts for its ability to lower IOP in young and aged mice.

in vivo

Trabodenoson (6.0%), demonstrating an average IOP drop of 2.45 ± 0.38 mm Hg in young mice over 7 days (downregulation)[1].
Topical trabodenoson significantly upregulates nestin expression in the ONH of induced eyes compared with vehicle-treated no-induced eyes[2].
Trabodenoson-treated eyes have significantly reduced optic nerve (ON) edema compared with vehicle-treated eyes. RGC counts are higher in Trabodenoson-treated eyes compared to vehicle (74% versus 47% of the contralateral eye)[2].

Animal Model:Young (3-4 months old) and aged (12 months old)[1].
Dosage:3% or 6% in 10 μL.
Administration:Eye drop for 7 consecutive days.
Result:Decreased IOP.
Animal Model:Rats[2].
Dosage:3%.
Administration:Topical delivery daily.
Result:Had significantly reduced optic nerve (ON) edema.

trabodenoson Preparation Products And Raw materials

Raw materials

Preparation Products

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trabodenoson Suppliers

China 23 United States 5 Global 28
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
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China
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2922
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Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
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58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
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Shanghai Biopharmaleader Co., Ltd.
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+86 18721201413
Fax
+86 (21) 5775-8967
Email
sales@biopharmaleader.com
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China
ProdList
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Chengdu Saint - Kay Biotechnology Co., Ltd.
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028-85157043 15882256948
Email
676046971@qq.com
Country
China
ProdList
4181
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58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
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58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
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58
Suzhou Chenrui Biotechnology Co. LTD
Tel
17625585511
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qq：1580084073
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1580084073@qq.com
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China
ProdList
959
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58
Advanced chemblocks inc
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650-6922368
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sales@achemblock.com
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China
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Wuhan Topule
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+86-02787215551 +86-19945035818
Fax
027-87215551
Email
2936752263@qq.com
Country
China
ProdList
7993
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871108-05-3, trabodenosonRelated Search:


  • trabodenoson
  • ((2R,3S,4R,5R)-5-(6-(CYCLOPENTYLAMINO)-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHYL NITRATE
  • Adenosine, N-cyclopentyl-, 5'-nitrate
  • INO-8875
  • INNO-8875
  • N-Cyclopentyladenosine 5'-nitrate
  • PJ 875
  • Trabodenoson, 10 mM in DMSO
  • 871108-05-3
  • C15H20N6O6