trabodenoson
- Product Name
- trabodenoson
- CAS No.
- 871108-05-3
- Chemical Name
- trabodenoson
- Synonyms
- PJ 875;INO-8875;INNO-8875;trabodenoson;Trabodenoson, 10 mM in DMSO;N-Cyclopentyladenosine 5'-nitrate;Adenosine, N-cyclopentyl-, 5'-nitrate;((2R,3S,4R,5R)-5-(6-(CYCLOPENTYLAMINO)-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHYL NITRATE
- CBNumber
- CB73067203
- Molecular Formula
- C15H20N6O6
- Formula Weight
- 380.36
- MOL File
- 871108-05-3.mol
trabodenoson Property
- Boiling point:
- 691.2±65.0 °C(Predicted)
- Density
- 1.87±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO: soluble
- form
- A crystalline solid
- pka
- 12.99±0.70(Predicted)
- color
- White to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-0024616
- Product name
- Trabodenoson
- Purity
- 98.14%
- Packaging
- 5mg
- Price
- $400
- Updated
- 2021/12/16
- Product number
- CD70000284
- Product name
- Trabodenoson
- Purity
- 97%
- Packaging
- 50mg
- Price
- $430
- Updated
- 2021/12/16
- Product number
- CD70000284
- Product name
- Trabodenoson
- Purity
- 97%
- Packaging
- 250mg
- Price
- $1292
- Updated
- 2021/12/16
trabodenoson Chemical Properties,Usage,Production
Uses
Trabodenoson alters ECM turnover by TM cells and increases conventional outflow facility, which accounts for its ability to lower IOP in young and aged mice.
in vivo
Trabodenoson (6.0%), demonstrating an average IOP drop of 2.45 ± 0.38 mm Hg in young mice over 7 days (downregulation)[1].
Topical trabodenoson significantly upregulates nestin expression in the ONH of induced eyes compared with vehicle-treated no-induced eyes[2].
Trabodenoson-treated eyes have significantly reduced optic nerve (ON) edema compared with vehicle-treated eyes. RGC counts are higher in Trabodenoson-treated eyes compared to vehicle (74% versus 47% of the contralateral eye)[2].
| Animal Model: | Young (3-4 months old) and aged (12 months old)[1]. |
| Dosage: | 3% or 6% in 10 μL. |
| Administration: | Eye drop for 7 consecutive days. |
| Result: | Decreased IOP. |
| Animal Model: | Rats[2]. |
| Dosage: | 3%. |
| Administration: | Topical delivery daily. |
| Result: | Had significantly reduced optic nerve (ON) edema. |
trabodenoson Preparation Products And Raw materials
Raw materials
Preparation Products
trabodenoson Suppliers
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