N106

Product Name: N106
CAS No.: 862974-25-2
Chemical Name: N106
Synonyms: N106, 10 mM in DMSO;4-Methoxy-N-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl-2-benzothiazolamine;2-Benzothiazolamine, 4-methoxy-N-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-;N-(4-Methoxybenzo[d]thiazol-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-amine
CBNumber: CB73146335
Molecular Formula: C17H14N4O3S
Formula Weight: 354.38
MOL File: 862974-25-2.mol

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N106 Property

Boiling point:: 545.4±56.0 °C(Predicted)
Density: 1.390±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 20 mg/ml
form: A solid
pka: 1.03±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: N926030
Product name: N106
Packaging: 1mg
Price: $130
Updated: 2021/12/16

Axon Medchem

Product number: Axon2565
Product name: N106
Purity: 99%
Packaging: 25mg
Price: $368.5
Updated: 2021/12/16

AK Scientific

Product number: 0326CK
Product name: N-(4-Methoxybenzo[d]thiazol-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-amine
Packaging: 25mg
Price: $749
Updated: 2021/12/16

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N106 Chemical Properties,Usage,Production

Uses

N106 is an activator of SUMO-activating enzyme, E1 ligase.

in vivo

In a murine model, the half-life of N106 is determined to be ～65.4?min with a C_max of ～2.24?μM when the mice received 10?mg/kg of N106 by intravenous injection. The oral bioavailability (F%) is 56% and 50%, and terminal elimination half-life (t_1/2) is 19?min^[1].
? In vivo, N106 (10 mg/kg) increases cardiac SERCA2A SUMOylation, and significantly improves ventricular function in mice with heart failure^[1].

N106 Preparation Products And Raw materials

Raw materials

Preparation Products

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N106 Suppliers

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862974-25-2, N106Related Search:

N-(4-Methoxybenzo[d]thiazol-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-amine

4-Methoxy-N-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl-2-benzothiazolamine

2-Benzothiazolamine, 4-methoxy-N-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-

N106, 10 mM in DMSO

862974-25-2