Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester

Product Name: Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester
CAS No.: 88039-46-7
Chemical Name: Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester
Synonyms: INF 4E;NLRP3-IN-9, 10 mM in DMSO;Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate;Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester;Benzenepropanoic acid, 2-chloro-β-hydroxy-α-methylene-, ethyl ester;inflammasome,NOD-like Receptor (NLR),myocardial injury,NLRP3 IN 9,caspase-1,dysfunction,NLRP3IN9,Inhibitor,pyroptosis,inhibit,NLRP-3-IN-9,THP-1 cells
CBNumber: CB73270199
Molecular Formula: C12H13ClO3
Formula Weight: 240.68282
MOL File: 88039-46-7.mol

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Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Property

Boiling point:: 180-185 °C(Press: 10 Torr)
Density: 1.222±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 12.51±0.20(Predicted)
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 6172
Product name: INF4E
Purity: ≥98%(HPLC)
Packaging: 10
Price: $208
Updated: 2021/12/16

TRC

Product number: I496003
Product name: INF4E
Packaging: 1g
Price: $1010
Updated: 2021/12/16

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Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Chemical Properties,Usage,Production

Uses

INF 4E was used to study the electrophilic warhead-based design of compounds preventing NLRP3 inflammasome-dependent pyroptosis.

in vivo

INF4E significantly reduces the in infarct size and lactate dehydrogenase release and improvement in postischemic left ventricular pressure^[1].
INF4E attenuates the formation of NLRP3 inflammasome complex was induced by myocardial IR (ischemia/reperfusion) in a time-dependent way^[1].

IC 50

NLRP3

storage

Store at -20°C

Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Suppliers

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88039-46-7, Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl esterRelated Search:

Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester

Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate

INF 4E

inflammasome,NOD-like Receptor (NLR),myocardial injury,NLRP3 IN 9,caspase-1,dysfunction,NLRP3IN9,Inhibitor,pyroptosis,inhibit,NLRP-3-IN-9,THP-1 cells

Benzenepropanoic acid, 2-chloro-β-hydroxy-α-methylene-, ethyl ester

NLRP3-IN-9, 10 mM in DMSO

88039-46-7