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Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester

Product Name
Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester
CAS No.
88039-46-7
Chemical Name
Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester
Synonyms
INF 4E;NLRP3-IN-9, 10 mM in DMSO;Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate;Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester;Benzenepropanoic acid, 2-chloro-β-hydroxy-α-methylene-, ethyl ester;inflammasome,NOD-like Receptor (NLR),myocardial injury,NLRP3 IN 9,caspase-1,dysfunction,NLRP3IN9,Inhibitor,pyroptosis,inhibit,NLRP-3-IN-9,THP-1 cells
CBNumber
CB73270199
Molecular Formula
C12H13ClO3
Formula Weight
240.68282
MOL File
88039-46-7.mol
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Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Property

Boiling point:
180-185 °C(Press: 10 Torr)
Density 
1.222±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
12.51±0.20(Predicted)
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
6172
Product name
INF4E
Purity
≥98%(HPLC)
Packaging
10
Price
$208
Updated
2021/12/16
TRC
Product number
I496003
Product name
INF4E
Packaging
1g
Price
$1010
Updated
2021/12/16
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Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Chemical Properties,Usage,Production

Uses

INF 4E was used to study the electrophilic warhead-based design of compounds preventing NLRP3 inflammasome-dependent pyroptosis.

in vivo

INF4E significantly reduces the in infarct size and lactate dehydrogenase release and improvement in postischemic left ventricular pressure[1].
INF4E attenuates the formation of NLRP3 inflammasome complex was induced by myocardial IR (ischemia/reperfusion) in a time-dependent way[1].

IC 50

NLRP3

storage

Store at -20°C

Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Suppliers

China 27 United Kingdom 1 United States 2 Global 30
Tocris Bioscience
Tel
--
Fax
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Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77

88039-46-7, Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl esterRelated Search:


  • Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester
  • Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate
  • INF 4E
  • inflammasome,NOD-like Receptor (NLR),myocardial injury,NLRP3 IN 9,caspase-1,dysfunction,NLRP3IN9,Inhibitor,pyroptosis,inhibit,NLRP-3-IN-9,THP-1 cells
  • Benzenepropanoic acid, 2-chloro-β-hydroxy-α-methylene-, ethyl ester
  • NLRP3-IN-9, 10 mM in DMSO
  • 88039-46-7