ChemicalBook > CAS DataBase List > EOS-62353
EOS-62353
- Product Name
- EOS-62353
- CAS No.
- 1657014-42-0
- Chemical Name
- EOS-62353
- Synonyms
- EOS-62353;GDC-0575 2HCl;GDC-0575 dihydrochloride
- CBNumber
- CB73362760
- Molecular Formula
- C16H21BrClN5O
- Formula Weight
- 414.73
- MOL File
- 1657014-42-0.mol
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EOS-62353 Property
- storage temp.
- Store at -20°C
- solubility
- DMSO : 65 mg/mL (144.06 mM)
- form
- Solid
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0047717
- Product name
- GDC-0575dihydrochloride
- Purity
- 99.83%
- Packaging
- 5mg
- Price
- $210
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0047717
- Product name
- GDC-0575dihydrochloride
- Purity
- 99.83%
- Packaging
- 10mg
- Price
- $360
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0047717
- Product name
- GDC-0575dihydrochloride
- Purity
- 99.83%
- Packaging
- 25mg
- Price
- $720
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0047717
- Product name
- GDC-0575dihydrochloride
- Purity
- 99.83%
- Packaging
- 50mg
- Price
- $1200
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0047717
- Product name
- GDC-0575dihydrochloride
- Purity
- 99.83%
- Packaging
- 100mg
- Price
- $2100
- Updated
- 2021/12/16
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EOS-62353 Chemical Properties,Usage,Production
Description
GDC-0575, also known as ARRY-575 and RG7741, is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2?nM. Chk1 inhibitor GDC-0575 specifically binds to and inhibits Chk1; this may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M phases, which permits the cells to undergo DNA repair prior to entry into mitosis.
EOS-62353 Preparation Products And Raw materials
Raw materials
Preparation Products
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EOS-62353 Suppliers
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- China
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