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EOS-62353

Product Name
EOS-62353
CAS No.
1657014-42-0
Chemical Name
EOS-62353
Synonyms
EOS-62353;GDC-0575 2HCl;GDC-0575 dihydrochloride
CBNumber
CB73362760
Molecular Formula
C16H21BrClN5O
Formula Weight
414.73
MOL File
1657014-42-0.mol
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EOS-62353 Property

storage temp. 
Store at -20°C
solubility 
DMSO : 65 mg/mL (144.06 mM)
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0047717
Product name
GDC-0575dihydrochloride
Purity
99.83%
Packaging
5mg
Price
$210
Updated
2021/12/16
ChemScene
Product number
CS-0047717
Product name
GDC-0575dihydrochloride
Purity
99.83%
Packaging
10mg
Price
$360
Updated
2021/12/16
ChemScene
Product number
CS-0047717
Product name
GDC-0575dihydrochloride
Purity
99.83%
Packaging
25mg
Price
$720
Updated
2021/12/16
ChemScene
Product number
CS-0047717
Product name
GDC-0575dihydrochloride
Purity
99.83%
Packaging
50mg
Price
$1200
Updated
2021/12/16
ChemScene
Product number
CS-0047717
Product name
GDC-0575dihydrochloride
Purity
99.83%
Packaging
100mg
Price
$2100
Updated
2021/12/16
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EOS-62353 Chemical Properties,Usage,Production

Description

GDC-0575, also known as ARRY-575 and RG7741, is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2?nM. Chk1 inhibitor GDC-0575 specifically binds to and inhibits Chk1; this may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M phases, which permits the cells to undergo DNA repair prior to entry into mitosis.

EOS-62353 Preparation Products And Raw materials

Raw materials

Preparation Products

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EOS-62353 Suppliers

InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58

1657014-42-0, EOS-62353Related Search:


  • EOS-62353
  • GDC-0575 dihydrochloride
  • GDC-0575 2HCl
  • 1657014-42-0