2-Fluoro-6-nitrophenol
- Product Name
- 2-Fluoro-6-nitrophenol
- CAS No.
- 1526-17-6
- Chemical Name
- 2-Fluoro-6-nitrophenol
- Synonyms
- 2-Fluoro-6-nitrophen;2-Fluor-6-nitro-phenol;6-FLUORO-2-NITROPHENOL;2-FLUORO-6-NITROPHENOL;2-NITRO-6-FLUORO PHENOL;fluoro-2 nitro-6 phenol;Phenol,2-fluoro-6-nitro-;Fluoro-6-nitrophenol, 2-;2-Fluoro-6-nitrophenol98%;2-Fluoro-6-nitrophenol>
- CBNumber
- CB7371453
- Molecular Formula
- C6H4FNO3
- Formula Weight
- 157.1
- MOL File
- 1526-17-6.mol
2-Fluoro-6-nitrophenol Property
- Melting point:
- 92-94°C
- Boiling point:
- 201.5±20.0 °C(Predicted)
- Density
- 1.511±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 5.67±0.24(Predicted)
- color
- Light yellow to Yellow to Orange
- BRN
- 1870307
- InChI
- InChI=1S/C6H4FNO3/c7-4-2-1-3-5(6(4)9)8(10)11/h1-3,9H
- InChIKey
- HIGRXCJEFUYRNW-UHFFFAOYSA-N
- SMILES
- C1(O)=C([N+]([O-])=O)C=CC=C1F
- CAS DataBase Reference
- 1526-17-6(CAS DataBase Reference)
- EPA Substance Registry System
- 2-Fluoro-6-nitrophenol (1526-17-6)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36/37/39-36/37
- RIDADR
- 2811
- HazardClass
- IRRITANT
- PackingGroup
- III
- HS Code
- 29089990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H301Toxic if swalloed
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- F0623
- Product name
- 2-Fluoro-6-nitrophenol
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $32
- Updated
- 2025/07/31
- Product number
- F0623
- Product name
- 2-Fluoro-6-nitrophenol
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $95
- Updated
- 2025/07/31
- Product number
- F594845
- Product name
- 2-Fluoro-6-nitrophenol
- Packaging
- 25g
- Price
- $470
- Updated
- 2021/12/16
- Product number
- F594845
- Product name
- 2-Fluoro-6-nitrophenol
- Packaging
- 10g
- Price
- $230
- Updated
- 2021/12/16
- Product number
- HCH0019920
- Product name
- 2-FLUORO-6-NITROPHENOL
- Purity
- 95.00%
- Packaging
- 100G
- Price
- $2609.15
- Updated
- 2021/12/16
2-Fluoro-6-nitrophenol Chemical Properties,Usage,Production
Uses
2-Fluoro-6-nitrophenol has antifungal- and high plant-growth-regulating activity.
Synthesis
367-12-4
7440-44-0
1526-17-6
403-19-0
A. Synthesis of 2-fluoro-4-nitrophenol To a stirred dichloromethane solution of 2-fluorophenol (32.3 g, 0.288 mol) was slowly added 90% nitric acid (1 g, 0.31 mol HNO3) in an ice-salt bath cooled to -10°C. The addition process was controlled to be completed in 1 hour. During the reaction, the temperature was maintained at about -5 °C. After the addition was completed, stirring was continued at 0°C for 1 hour. At the end of the reaction, the precipitate was collected by filtration and washed several times with cold dichloromethane. Analysis by GC and thin layer chromatography (silica gel, 7:3 hexane-acetone) showed that the product was mainly a single compound and that the by-products produced in the reaction were of low polarity and volatility. The solid was dissolved in ether, washed with water, dried (MgSO4) and the solvent evaporated. The resulting solid was recrystallized with methylcyclohexane to give 13 g of a pale yellow solid with a melting point of 119°-121°C. NMR (CDCl3) analysis confirmed the product as 2-fluoro-4-nitrophenol. The dichloromethane mother liquor was treated, washed with water, dried (MgSO4) and the solvent evaporated. The solid obtained was ground with boiling hexane (3 x 150 ml) to effectively remove the least polar and highly volatile reaction by-products. The hexane solution was treated with activated charcoal, filtered and concentrated to about 300 ml and cooled to give 13.5 g (30% yield) of the by-product 2-fluoro-6-nitrophenol as a yellow solid with a melting point of 70°-86 °C.
References
[1] Patent: US4750931, 1988, A
[2] Patent: EP142328, 1991, B1
2-Fluoro-6-nitrophenol Preparation Products And Raw materials
Raw materials
Preparation Products
2-Fluoro-6-nitrophenol Suppliers
- Tel
- --
- Fax
- --
- sales@riccichimica.com
- Country
- Italy
- ProdList
- 2146
- Advantage
- 46
View Lastest Price from 2-Fluoro-6-nitrophenol manufacturers
- Product
- 2-Fluoro-6-nitrophenol 1526-17-6
- Price
- US $8.00-0.80/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-01-22
- Product
- 2-Fluoro-6-nitrophenol 1526-17-6
- Price
- US $10.00/Kg/Bag
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10Tons
- Release date
- 2021-07-20
- Product
- 2-Fluoro-6-nitrophenol 1526-17-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-08