ChemicalBook > CAS DataBase List > SB 218795

SB 218795

Product Name
SB 218795
CAS No.
174635-53-1
Chemical Name
SB 218795
Synonyms
SB 218795;Sb 218795r;Methyl (R)-2-phenyl-2-(2-phenylquinoline-4-carboxamido)acetate;methyl (2R)-2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate;(-)-(R)-N-(α-Methoxycarbonylbenzyl)-2-phenylquinoline-4-carboxamide;(-)-(R)-N-(ALPHA-METHOXYCARBONYLBENZYL)-2-PHENYLQUINOLINE-4-CARBOXAMIDE;(R)-[[(2-PHENYL-4-QUINOLINYL)CARBONYL]AMINO]-METHYL ESTER BENZENEACETIC ACID;Benzeneacetic acid, α-[[(2-phenyl-4-quinolinyl)carbonyl]amino]-, methyl ester, (αR)-;Benzeneacetic acid, alpha-(((2-phenyl-4-quinolinyl)carbonyl)amino)-, methyl ester, (alphar)-;constriction,SB-218795,Neurokinin Receptor,Inhibitor,neurokinin-3,NK receptor,pupillary,inhibit,Tachykinin receptor,SB218795,SB 218795,NK-3
CBNumber
CB7376630
Molecular Formula
C25H20N2O3
Formula Weight
396.44
MOL File
174635-53-1.mol
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SB 218795 Property

Boiling point:
623.7±55.0 °C(Predicted)
Density 
1.237±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 40 mg/mL, soluble
form 
solid
pka
11.41±0.46(Predicted)
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1376
Product name
SB218795
Purity
≥99%(HPLC)
Packaging
10
Price
$174
Updated
2021/12/16
Tocris
Product number
1376
Product name
SB218795
Purity
≥99%(HPLC)
Packaging
50
Price
$713
Updated
2021/12/16
TRC
Product number
S155070
Product name
SB218795
Packaging
50mg
Price
$865
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007579
Product name
SB 218795
Purity
95.00%
Packaging
50MG
Price
$1327.97
Updated
2021/12/16
ApexBio Technology
Product number
B6710
Product name
SB218795
Packaging
50mg
Price
$1362
Updated
2021/12/16
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SB 218795 Chemical Properties,Usage,Production

Uses

SB 218795 is an NK3 receptor antagonist.

Definition

ChEBI: (2R)-2-[[oxo-(2-phenyl-4-quinolinyl)methyl]amino]-2-phenylacetic acid methyl ester is a member of quinolines.

Biological Activity

Potent, selective and competitive non-peptide NK 3 receptor antagonist (K i = 13 nM at hNK 3 ). Displays 90-fold and 7000-fold selectivity over hNK 2 and hNK 1 receptors respectively. Active in vivo , inhibiting agonist-induced pupillary constriction.

SB 218795 Preparation Products And Raw materials

Raw materials

Preparation Products

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SB 218795 Suppliers

China 26 Germany 1 Switzerland 1 United Kingdom 1 United States 5 Global 34
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
ApexBio Technology
Tel
--
Fax
--
Email
sales@apexbt.com
Country
United States
ProdList
6251
Advantage
58
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87

174635-53-1, SB 218795Related Search:

CHEMBRDG-BB 9071014 SB 218795 N-(2-HYDROXYETHYL)ISONICOTINAMIDE, 99 FOR-D-PHG-OH N-METHYL-1-QUINOLIN-4-YLMETHANAMINE N-ME-D-PHG-OH 2-methylquinoline-4-carboxamide D(-)-AC-ALPHA-PHENYLGLYCINOL

  • SB 218795
  • (-)-(R)-N-(ALPHA-METHOXYCARBONYLBENZYL)-2-PHENYLQUINOLINE-4-CARBOXAMIDE
  • (R)-[[(2-PHENYL-4-QUINOLINYL)CARBONYL]AMINO]-METHYL ESTER BENZENEACETIC ACID
  • (-)-(R)-N-(α-Methoxycarbonylbenzyl)-2-phenylquinoline-4-carboxamide
  • Benzeneacetic acid, alpha-(((2-phenyl-4-quinolinyl)carbonyl)amino)-, methyl ester, (alphar)-
  • Sb 218795r
  • methyl (2R)-2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate
  • constriction,SB-218795,Neurokinin Receptor,Inhibitor,neurokinin-3,NK receptor,pupillary,inhibit,Tachykinin receptor,SB218795,SB 218795,NK-3
  • Benzeneacetic acid, α-[[(2-phenyl-4-quinolinyl)carbonyl]amino]-, methyl ester, (αR)-
  • Methyl (R)-2-phenyl-2-(2-phenylquinoline-4-carboxamido)acetate
  • 174635-53-1