7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE

Product Name: 7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE
CAS No.: 6742-12-7
Chemical Name: 7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE
Synonyms: formycin;NSC 102811;formycin A;FORMYCIN MONOHYDRATE;FORMYCIN A MONOHYDRATE;8-Aza-9-deazaadenosine;8-AZA-9-DEAZAADENOSINE MONOHYDRATE;3-β-D-Ribofuranosyl-1H-pyrazolo[4,3-d]pyrimidine-7-amine;3-(β-D-Ribofuranosyl)-1H-pyrazolo[4,3-d]pyrimidin-7-amine;3-d)pyrimidine,7-amino-3-beta-d-ribofuranosyl-1h-pyrazolo(
CBNumber: CB7395563
Molecular Formula: C10H13N5O4
Formula Weight: 267.25
MOL File: 6742-12-7.mol

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7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE Property

Melting point:: 141-144 °C (decomp)
Boiling point:: 709.5±60.0 °C(Predicted)
Density: 1.771±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO: soluble1mg/mL
form: powder
pka: 8.37±0.50(Predicted)
color: white to off-white
BRN: 624229

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 22-24/25
WGK Germany: 3
RTECS: UR0719000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SMB00287
Product name: Formycin A
Purity: from
Packaging: 10mg
Price: $416.78
Updated: 2025/07/31

American Custom Chemicals Corporation

Product number: API0010090
Product name: FORMYCIN A
Purity: 95.00%
Packaging: 10MG
Price: $407.4
Updated: 2021/12/16

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7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE Chemical Properties,Usage,Production

Description

Formycin (Formycin A) is isolated from Nocardia interforma and from Streptomyces lavendulae , . The antibiotic is effective against Xanthomonas oryzae and Pellicularia filamentosa. Its activity against Yoshida rat sarcoma cell is enhanced by coformycin. Formycin B inhibits Xanthomonas oryzae and interferes with multiplication of influenza A virus in the cells of chick chorioallantoic membrane . Oxoformycin B shows no activity against Xanthomonas oryzae .

Uses

Formycin A (NSC 102811), a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM. Formycin A shows antitumor and antiviral activities[1][2].

Definition

ChEBI: Formycin A is a formycin. It has a role as an antineoplastic agent.

IC 50

HIV-1: 10 μM (EC₅₀)

References

[1] Dapp MJ , et al. Discovery of novel ribonucleoside analogs with activity against human immunodeficiency virus type 1.J Virol. 2014 Jan;88(1):354-63. DOI:10.1128/JVI.02444-13
[2] Zhang M, et al. Comparative Investigation into Formycin A and Pyrazofurin A Biosynthesis Reveals Branch Pathways for the Construction of C-Nucleoside Scaffolds. Appl Environ Microbiol. 2020 Jan 7;86(2). DOI:10.1128/AEM.01971-19

7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE Suppliers

China 20 Switzerland 1 United States 8 Global 29

TargetMol Chemicals Inc.

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BOC Sciences

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BOC Sciences

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Aladdin Scientific

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Berry & Associates, Inc.

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6742-12-7, 7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATERelated Search:

Doxycycline Spectinomycin Oxytetracycline Gentamicin (1H-PYRAZOL-3-YL)METHANOL 2,2'-Oxydipropanol 7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE 2,5-DIMETHYLTETRAHYDROFURAN

3-d)pyrimidin-3-yl)-1,4-anhydro-1-c-(7-amino-1h-pyrazolo((s)-d-ribito

3-d)pyrimidine,7-amino-3-beta-d-ribofuranosyl-1h-pyrazolo(

7-amino-3-beta-d-ribofuranosyl-1h-pyrazolo(4,3-d)pyrimidine

formycin

8-AZA-9-DEAZAADENOSINE MONOHYDRATE

7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE

FORMYCIN MONOHYDRATE

FORMYCIN A MONOHYDRATE

(1S)-1-C-(7-Amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol

3-(β-D-Ribofuranosyl)-1H-pyrazolo[4,3-d]pyrimidin-7-amine

3-β-D-Ribofuranosyl-1H-pyrazolo[4,3-d]pyrimidine-7-amine

1-C-(7-Amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-, (1S)-

8-Aza-9-deazaadenosine

NSC 102811

formycin A

7-Amino-3-(β-D-ribofuranosyl)-1H-pyrazolo[4,3-d]pyrimidine

D-Ribitol, 1-C-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-, (1S)-

7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRAT

6742-12-7