5-CARBOXYOXINDOLE

Product Name: 5-CARBOXYOXINDOLE
CAS No.: 102359-00-2
Chemical Name: 5-CARBOXYOXINDOLE
Synonyms: 5-CARBOXYOXINDOLE;RARECHEM AL BO 0983;5-CARBOXY-2-OXINDOLE;5-Carboxyindol-2-one;5-Carboxyoxindole 97%;5-Carboxyl-2-oxindole;OXINDOLE-5-CARBOXYLIC ACID;2-Oxindole-5-carboxylic a...;2-Oxindole-5-carboxylic acid;2-Oxindole-5-carboxylic acid 97%
CBNumber: CB7399031
Molecular Formula: C9H7NO3
Formula Weight: 177.16
MOL File: 102359-00-2.mol

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5-CARBOXYOXINDOLE Property

Melting point:: 310-316°C
Boiling point:: 459.8±45.0 °C(Predicted)
Density: 1.433±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
form: Solid
pka: 4.19±0.20(Predicted)
color: Off-White to Light Orange
InChI: InChI=1S/C9H7NO3/c11-8-4-6-3-5(9(12)13)1-2-7(6)10-8/h1-3H,4H2,(H,10,11)(H,12,13)
InChIKey: LLLKBUWXODIMEW-UHFFFAOYSA-N
SMILES: N1C2=C(C=C(C(O)=O)C=C2)CC1=O
CAS DataBase Reference: 102359-00-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-43
Safety Statements: 26-36/37/39-36/37
Hazard Note: Irritant
HS Code: 2933790090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC

Product number: C178933
Product name: 5-Carboxyoxindole
Packaging: 250mg
Price: $80
Updated: 2021/12/16

Apolloscientific

Product number: OR10403
Product name: 2-Oxindole-5-carboxylic acid
Purity: 97%
Packaging: 5g
Price: $211
Updated: 2021/12/16

Apolloscientific

Product number: OR10403
Product name: 2-Oxindole-5-carboxylic acid
Purity: 97%
Packaging: 250mg
Price: $22
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H48-1-E9
Product name: 2-Oxindole-5-carboxylic acid
Purity: 97%
Packaging: 250mg
Price: $26
Updated: 2021/12/16

Apolloscientific

Product number: OR10403
Product name: 2-Oxindole-5-carboxylic acid
Purity: 97%
Packaging: 1g
Price: $56
Updated: 2021/12/16

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5-CARBOXYOXINDOLE Chemical Properties,Usage,Production

Synthesis

65435-04-3

102359-00-2

The general procedure for the synthesis of 2-oxoindoline-5-carboxylic acid from 5-chloroacetylindone was as follows (Example 13, from Table 3): 6.7 g of 2-hydroxyindole acid was slowly added to a stirred suspension of 30 mL of dichloroethane containing 23 g of aluminum chloride under ice bath conditions. Subsequently, 11.3 g of chloroacetyl chloride was slowly added dropwise, during which hydrogen chloride gas was released. The reaction mixture was stirred for 10 minutes and then gradually warmed to 40-50°C and maintained at this temperature for 1.5 hours. The progress of the reaction was monitored by thin layer chromatography (unfolding agent: ethyl acetate, stationary phase: silica gel) to confirm complete consumption of the raw materials. Upon completion of the reaction, the mixture was cooled to room temperature and carefully poured into ice water. The resulting precipitate was collected by vacuum filtration, washed with water and dried under vacuum to give 10.3 g (98% yield) of 5-chloroacetyl-2-hydroxyindole as an off-white solid.

References

[1] Patent: US6878733, 2005, B1. Location in patent: Page/Page column 220
[2] Patent: US6878733, 2005, B1. Location in patent: Page/Page column 172
[3] Patent: US6350754, 2002, B2. Location in patent: Page column 24
[4] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 3, p. 745 - 750
[5] Chemical and Pharmaceutical Bulletin, 1988, vol. 36, # 6, p. 2253 - 2258

5-CARBOXYOXINDOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-CARBOXYOXINDOLE Suppliers

China 88 France 1 Germany 4 India 3 United Kingdom 5 United States 15 Global 116

Tianjin Derchemist Science & Technology Co., Ltd.

Tel: 22-58627059 13920586291
Fax: 022-58620305
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Advantage: 50

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
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Wuhan Chemwish Technology Co., Ltd

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Country: China
ProdList: 35896
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Capot Chemical Co., Ltd

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Fax: 0086-571-85864795
Country: China
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Accela ChemBio Co.,Ltd.

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Country: China
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Nanjing Chemlin Chemical Co., Ltd

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ProdList: 15883
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China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
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SpringPharma Tech Co.,Ltd

Tel: +86-25-68710855, +86-25-68710897
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Advantage: 62

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

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View Lastest Price from 5-CARBOXYOXINDOLE manufacturers

Chemwill Asia Co.,Ltd.

Product: 5-Carboxyl-2-oxindole ; 5-CARBOXYOXINDOLE; in stock Factory 102359-00-2
Price: US $1.00/kg
Min. Order: 1kg
Purity: High quality purified Factory in China
Supply Ability: Top 3 production capacity Factory
Release date: 2019-04-03

Career Henan Chemical Co

Product: 5-CARBOXYOXINDOLE 102359-00-2
Price: US $5.50/KG
Min. Order: 1KG
Purity: 98%-99%
Supply Ability: 1kg-100kg
Release date: 2020-01-07

102359-00-2, 5-CARBOXYOXINDOLERelated Search:

6-CARBOXYOXINDOLE Methyl oxindole-5-carboxylate 5-NITRO-1(2H)-ISOQUINOLINONE Ethyl 2-oxoindoline-5-carboxylate Oxindole 5-CARBOXYOXINDOLE 7-Carboxyoxindole 1-methyl-2-oxoindoline-5-carboxylic acid 4-Carboxyoxindole 5-CARBOXYISATIN METHYL ESTER 2,3-DIOXOINDOLINE-5-CARBOXYLIC ACID 1-ACETYL-2-OXO-2,3-DIHYDRO-1H-INDOLE-5-CARBOXYLIC ACID METHYL ESTER 5-ETHOXYCARBONYL-3-HYDROXY-2-OXO-3-(TRIFLUOROMETHYL)INDOLINE

5-CARBOXYOXINDOLE

RARECHEM AL BO 0983

OXINDOLE-5-CARBOXYLIC ACID

2-Oxo-indoline-5-carboxylic acid

2-oxo-2,3,3a,7a-tetrahydro-1H-indole-6-carboxylic acid

2-oxo-1,3-dihydroindole-5-carboxylate

5-CARBOXY-2-OXINDOLE

5-Carboxyoxindole 97%

2-Oxindole-5-carboxylic acid

2-Oxindole-5-carboxylic a...

2-Oxindole-5-carboxylic acid 97%

5-Carboxyindolin-2-one, 2,3-Dihydro-2-oxo-1H-indole-5-carboxylic acid

1H-indol-5-yl hydrogen carbonate

5-Carboxyl-2-oxindole

1H-Indole-5-carboxylic acid, 2,3-dihydro-2-oxo-

5-Carboxyindol-2-one

102359-00-2

blocks

Carboxes

IndolesOxindoles

Indoline & Oxindole