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BMS-8

Product Name
BMS-8
CAS No.
1675201-90-7
Chemical Name
BMS-8
Synonyms
BMS-8;BMS-8, 10 mM in DMSO;PPI,BMS 8,BMS8,inhibit,BMS-8,Inhibitor,PD-L1,PD-1;1-(3-bromo-4-((2-methylbiphenyl-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid;1-(3-Bromo-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid;2-Piperidinecarboxylic acid, 1-[[3-bromo-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-
CBNumber
CB74666331
Molecular Formula
C27H28BrNO3
Formula Weight
494.42
MOL File
1675201-90-7.mol
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BMS-8 Property

Boiling point:
616.9±55.0 °C(Predicted)
Density 
1.334±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Methanol: slightly soluble
form 
A crystalline solid
pka
2.35±0.20(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22355
Product name
BMS-8
Purity
≥98%
Packaging
1mg
Price
$26
Updated
2024/03/01
Cayman Chemical
Product number
22355
Product name
BMS-8
Purity
≥98%
Packaging
25mg
Price
$542
Updated
2024/03/01
Cayman Chemical
Product number
22355
Product name
BMS-8
Purity
≥98%
Packaging
500μg
Price
$25
Updated
2021/12/16
Cayman Chemical
Product number
22355
Product name
BMS-8
Purity
≥98%
Packaging
5mg
Price
$122
Updated
2024/03/01
Cayman Chemical
Product number
22355
Product name
BMS-8
Purity
≥98%
Packaging
10mg
Price
$230
Updated
2024/03/01
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BMS-8 Chemical Properties,Usage,Production

Description

BMS-8 is a small molecule inhibitor of the protein-protein interaction between programmed death protein 1 (PD-1) and its ligand programmed cell death ligand 1 (PD-L1) with an IC50 value of 146 nM in a homogeneous time-resolved fluorescence (HTRF) binding assay.

Uses

BMS-8 is inhibitor of the PD-1/PD-L1 interaction by inducing PD-L1 dimerization through PD-1 interacting surface, binding at a hydrophobic cavity formed upon PD-L1 dimerization.

BMS-8 Preparation Products And Raw materials

Raw materials

Preparation Products

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BMS-8 Suppliers

China 24 United States 4 Global 28
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81

1675201-90-7, BMS-8Related Search:


  • BMS-8
  • 2-Piperidinecarboxylic acid, 1-[[3-bromo-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-
  • 1-(3-bromo-4-((2-methylbiphenyl-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid
  • PPI,BMS 8,BMS8,inhibit,BMS-8,Inhibitor,PD-L1,PD-1
  • 1-(3-Bromo-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid
  • BMS-8, 10 mM in DMSO
  • 1675201-90-7