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NSC117079

Product Name
NSC117079
CAS No.
500363-63-3
Chemical Name
NSC117079
Synonyms
NSC117079;NSC-117079,NSC117079;2-Anthracenesulfonic acid, 1-amino-4-[[3-(aminosulfonyl)phenyl]amino]-9,10-dihydro-9,10-dioxo-
CBNumber
CB74668294
Molecular Formula
C20H15N3O7S2
Formula Weight
473.48
MOL File
500363-63-3.mol
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NSC117079 Property

Density 
1.696±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 50 mg/mL (105.60 mM)
pka
-1.19±0.20(Predicted)
form 
Solid
color 
Pale purple to purple
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
N900415
Product name
NSC117079
Packaging
1mg
Price
$140
Updated
2021/12/16
TRC
Product number
N900415
Product name
NSC117079
Packaging
2.5mg
Price
$235
Updated
2021/12/16
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NSC117079 Chemical Properties,Usage,Production

Uses

NSC 117079, is a novel PHLPP inhibitor.

in vivo

A single intraarticular injection of the Phlpp inhibitor NSC117079 attenuates mechanical allodynia and slows articular cartilage degradation in joints with a destabilized meniscus. Animals treated with the Phlpp inhibitor seven weeks after injury maintain normal activity levels, while those in the control group travel shorter distances and are less active three months after the joint injury. NSC117079 also increases production of cartilage extracellular matrix components (glycosaminoglycans and aggrecan) in over 90% of human articular cartilage explants from osteoarthritis patients and increased phosphorylation of Phlpp1 substrates (AKT2, ERK1/2 and PKC) in human articular chondrocytes[1].

NSC117079 Preparation Products And Raw materials

Raw materials

Preparation Products

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NSC117079 Suppliers

China 24 United States 6 Global 30
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
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58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
TargetMol Chemicals Inc.
Tel
+17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
19962
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58

500363-63-3, NSC117079Related Search:


  • NSC117079
  • 2-Anthracenesulfonic acid, 1-amino-4-[[3-(aminosulfonyl)phenyl]amino]-9,10-dihydro-9,10-dioxo-
  • NSC-117079,NSC117079
  • 500363-63-3