5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE

Product Name: 5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE
CAS No.: 65156-94-7
Chemical Name: 5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE
Synonyms: 5-Chloro-4-azaindole;5-cChloro-1H-pyrrolo[3,2-b]pyridine;5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE;1H-Pyrrolo[3,2-b]pyridine, 5-chloro-;5-Chloro-4-azaindole,5-chloro-1H-pyrrolo[3,2-b]pyridine
CBNumber: CB7704671
Molecular Formula: C7H5ClN2
Formula Weight: 152.58
MOL File: 65156-94-7.mol

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5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE Property

Boiling point:: 304.9±22.0 °C(Predicted)
Density: 1.425±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: solid
pka: 13.75±0.40(Predicted)
Appearance: Light brown to yellow Solid

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Safety

Hazard Codes: Xi
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: ADE000995
Product name: 5-Chloro-1H-pyrrolo[3,2-b]pyridine
Purity: Aldrich
Packaging: 1g
Price: $427
Updated: 2025/07/31

TRC

Product number: B418638
Product name: 5-cChloro-1H-pyrrolo[3,2-b]pyridine
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC38532
Product name: 5-Chloro-1H-pyrrolo[3,2-b]pyridine
Packaging: 250mg
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC38532
Product name: 5-Chloro-1H-pyrrolo[3,2-b]pyridine
Packaging: 500mg
Price: $160
Updated: 2021/12/16

Matrix Scientific

Product number: 026287
Product name: 5-Chloro-1H-pyrrolo[3,2-b]pyridine
Packaging: 500mg
Price: $198
Updated: 2021/12/16

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5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE Chemical Properties,Usage,Production

Uses

5-Chloro-1H-pyrrolo[3,2-B]pyridine can be used as an organic synthesis intermediate and a pharmaceutical intermediate, and is mainly used in laboratory research and development processes and chemical pharmaceutical production processes.

Synthesis

1420070-26-3

65156-94-7

General procedure for the synthesis of 5-chloro-1H-pyrrolo[3,2-B]pyridine from compound (CAS:1420070-26-3): 5-chloro-1H-pyrrolo[3,2-B]pyridine (1.01 g, 5.1 mmol) was dissolved in 20 mL of methanol. 1 mL of concentrated hydrochloric acid was added and the reaction mixture was stirred at 75 °C for 21 hours. After completion of the reaction, the solvent was removed by evaporation under reduced pressure and the residue was extracted by partitioning with saturated potassium carbonate solution and ethyl acetate. The organic layer was dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. Purification by fast column chromatography (eluent: ethyl acetate/hexane, 33:67, v/v) afforded 0.55 g (3.6 mmol, 71% yield) of the target product, 5-chloro-1H-pyrrolo[3,2-B]pyridine, as a light yellow solid with 95% purity.1H NMR (300 MHz, CDCl3 + DMSO-d6) δ 9.85 (br. s , 1H), 7.67 (d, J = 8.5 Hz, 1H), 7.47 (m, 1H), 7.10 (d, J = 8.5 Hz, 1H), 6.65 (m, 1H).HPLC/MS analysis (run time 9 min) showed a retention time of 4.27 min. Low resolution mass spectrometry (LRMS): m/z 153 ([M + H]+).

References

[1] Patent: EP2548876, 2013, A1. Location in patent: Paragraph 0283-0286
[2] Patent: WO2013/10880, 2013, A1. Location in patent: Page/Page column 83

5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE Suppliers

China 136 Germany 1 India 1 United Kingdom 2 United States 14 Global 154

Pure Chemistry Scientific Inc.

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Synthonix

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View Lastest Price from 5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE 65156-94-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE 65156-94-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: 5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE 65156-94-7
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-10

65156-94-7, 5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINERelated Search:

ethyl 5-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylate 6-Chloro-1,3-dihydro-2H-pyrrolo[3,2-c]pyridin-2-one 1H-Pyrrolo[2,3-b]pyridine-3-carbonitrile, 5-chloro- 5-CHLORO (1H)INDAZOLE 5-chloro-1,2,3,4-tetrahydro-1,6-naphthyridine 5-Chloro-6-azaindole-3-carboxaldehyde 5-Chloro-1H-pyrazolo[4,3-b]pyridine 5-Chloro-1,2,3,4-tetrahydroisoquinoline 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE 5-Chloro-[1,2,4]triazolo[1,5-a]pyridine 5-CHLORO-3-HYDROXY (1H)INDAZOLE 5-CHLORO-1H-INDOL-3-METHYLAMINE 5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid 5-Chloro-1,3,4-thiadiazol-2-ylamine 6-Chloro-3H-1,2,3-triazolo[4,5-c]pyridine 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE 5-Chloro-7-azaindole-3-carboxaldehyde 5-Chloro-7-azaindole-3-carboxylic acid Methyl ester

5-Chloro-4-azaindole,5-chloro-1H-pyrrolo[3,2-b]pyridine

1H-Pyrrolo[3,2-b]pyridine, 5-chloro-

5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE

5-Chloro-4-azaindole

5-cChloro-1H-pyrrolo[3,2-b]pyridine

65156-94-7

Azaindoles