N-METHYL MESOPORPHYRIN IX

Product Name: N-METHYL MESOPORPHYRIN IX
CAS No.: 142234-85-3
Chemical Name: N-METHYL MESOPORPHYRIN IX
Synonyms: N-METHYL MESOPORPHYRIN IX;8,13-Diethyl-3,7,12,17,23-pentamethyl-21H,23H-porphine-2,18-dipropanoic acid;21H,23H-Porphine-2,18-dipropanoic acid, 8,13-diethyl-3,7,12,17,23-pentamethyl-;3,3'-(8,13-Diethyl-3,7,12,17,23-pentamethylporphyrin-2,18-diyl)dipropionic acid;21H,23H-Porphine-2,18-dipropanoic acid, 8,13-diethyl-3,7,12,17,23-pentamethyl- (9ci);3-[20-(2-carboxyethyl)-10,15-diethyl-5,9,14,19,22-pentamethyl-21,22,23,24-tetraazapentacyclo[16.2.1.13,?.1?,11.113,1?]tetracosa-1,3,5,7,9,11(23),12,14,16,18(21),19-undecaen-4-yl]propanoic acid
CBNumber: CB7749087
Molecular Formula: C35H40N4O4
Formula Weight: 580.72
MOL File: Mol file

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N-METHYL MESOPORPHYRIN IX Property

Density: 1.26±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:5): 0.17 mg/ml; DMSO: 15 mg/ml
form: A crystalline solid
color: Brown to black

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 27210
Product name: N-methyl Mesoporphyrin IX
Packaging: 1mg
Price: $93
Updated: 2024/03/01

Cayman Chemical

Product number: 27210
Product name: N-methyl Mesoporphyrin IX
Packaging: 5mg
Price: $208
Updated: 2024/03/01

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N-METHYL MESOPORPHYRIN IX Chemical Properties,Usage,Production

Uses

N-Methylmesoporphyrin IX (NMM), a widely used G-quadruplex DNA specific fluorescent binder, is an efficient probe for monitoring Aβ fibrillation. N-Methylmesoporphyrin IX is an in situ inhibitor and an ex situ monitor for Aβ amyloidogenesis both in vitro and in cells. N-Methylmesoporphyrin IX is sensitive to G-quadruplexes DNA but has no response to duplexes, triplexes and single-stranded forms DNA. N-Methylmesoporphyrin IX is nonfluorescent alone or in monomeric Aβ environments, but emits strong fluorescence through stacking with the Aβ assemblies[1].

References

[1] Meng Li, et al. N-Methyl Mesoporphyrin IX as an Effective Probe for Monitoring Alzheimer's Disease β-Amyloid Aggregation in Living Cells. ACS Chem Neurosci. 2017 Jun 21;8(6):1299-1304. DOI:10.1021/acschemneuro.6b00436

N-METHYL MESOPORPHYRIN IX Preparation Products And Raw materials

Raw materials

Preparation Products

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N-METHYL MESOPORPHYRIN IX Suppliers

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142234-85-3, N-METHYL MESOPORPHYRIN IXRelated Search:

N-METHYL MESOPORPHYRIN IX

21H,23H-Porphine-2,18-dipropanoic acid, 8,13-diethyl-3,7,12,17,23-pentamethyl-

21H,23H-Porphine-2,18-dipropanoic acid, 8,13-diethyl-3,7,12,17,23-pentamethyl- (9ci)

8,13-Diethyl-3,7,12,17,23-pentamethyl-21H,23H-porphine-2,18-dipropanoic acid

3,3'-(8,13-Diethyl-3,7,12,17,23-pentamethylporphyrin-2,18-diyl)dipropionic acid

3-[20-(2-carboxyethyl)-10,15-diethyl-5,9,14,19,22-pentamethyl-21,22,23,24-tetraazapentacyclo[16.2.1.13,?.1?,11.113,1?]tetracosa-1,3,5,7,9,11(23),12,14,16,18(21),19-undecaen-4-yl]propanoic acid

142234-85-3

Porphyrins