ChemicalBook > CAS DataBase List > 2,5-Dichloropyrimidine

2,5-Dichloropyrimidine

Product Name
2,5-Dichloropyrimidine
CAS No.
22536-67-0
Chemical Name
2,5-Dichloropyrimidine
Synonyms
EOS-60492;2,5-Dichlo;2,5-chloropyrimidine;2,5-DICHLOROPYRIMIDINE;Macitentan Impurity 32;2,5‐Dichloropyridimidine;2,5-Dichloro-1,3-diazine;Pyrimidine, 2,5-dichloro-;2,5-Dichloropyrimidine>2,5-Dichloropyrimidine 97%
CBNumber
CB7750461
Molecular Formula
C4H2Cl2N2
Formula Weight
148.98
MOL File
22536-67-0.mol
More
Less

2,5-Dichloropyrimidine Property

Melting point:
48-55 °C
Boiling point:
190°C
Density 
1.493
Flash point:
140°C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
-2.84±0.22(Predicted)
form 
Powder
color 
Off-white
Water Solubility 
Slightly soluble in water.
λmax
268nm(EtOH)(lit.)
InChI
InChI=1S/C4H2Cl2N2/c5-3-1-7-4(6)8-2-3/h1-2H
InChIKey
CEJAHXLRNZJPQH-UHFFFAOYSA-N
SMILES
C1(Cl)=NC=C(Cl)C=N1
CAS DataBase Reference
22536-67-0(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
C,N,Xn
Risk Statements 
22-41-50
Safety Statements 
26-39-61
RIDADR 
UN 3077 9/PG 3
WGK Germany 
2
HazardClass 
LACHRYMATOR, CORROSIVE
HazardClass 
9
PackingGroup 
Ⅲ
HS Code 
29335990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
720917
Product name
2,5-Dichloropyrimidine
Purity
97%
Packaging
1g
Price
$10.4
Updated
2024/03/01
TCI Chemical
Product number
D4045
Product name
2,5-Dichloropyrimidine
Purity
>98.0%(GC)
Packaging
5g
Price
$37
Updated
2024/03/01
TCI Chemical
Product number
D4045
Product name
2,5-Dichloropyrimidine
Purity
>98.0%(GC)
Packaging
25g
Price
$148
Updated
2024/03/01
Alfa Aesar
Product number
H64066
Product name
2,5-Dichloropyrimidine, 95%
Packaging
5g
Price
$32.65
Updated
2024/03/01
Alfa Aesar
Product number
H64066
Product name
2,5-Dichloropyrimidine, 95%
Packaging
25g
Price
$127.65
Updated
2024/03/01
More
Less

2,5-Dichloropyrimidine Chemical Properties,Usage,Production

Uses

2,5-Dichloropyrimidine acid is employed as a important raw material and intermediate used in organic synthesis agrochemical, pharmaceutical and dyestuff field.

Preparation

2,5-Dichloropyrimidine was synthesised from 2-hydroxypyrimidine hydrochloride by treatment with aqueous chlorine solution. Reaction of the product with phosphoryl chloride in the presence of N,N-dimethylaniline gave the desired product in 40% yield. The sample was then purified by sublimation.

storage

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

structure and hydrogen bonding

C4H2Cl2N2, M=148.98 monoclinic, space group P21/m with a=6.077(3), b=19.771(8), c=7.399(3) ?, β=101.23(6)°, U=872 ?3 [from 2θ values of 29 reflections measured at±ω, 25 ≤2θ ≤ 38°, λ = 0.710 73?, T=150.0 K], Dcalc=1.702 g cm-3, Z=6, μ =0.993 mm-1[1].

References

[1] Blake A, et al. Structure Analysis Restrained by ab Initio Calculations: The Molecular Structure of 2,5-Dichloropyrimidine in Gaseous and Crystalline Phases. The Journal of Physical Chemistry, 1996; 100: 12280–12287.

2,5-Dichloropyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2,5-Dichloropyrimidine Suppliers

Americas 1 Canada 3 China 239 Europe 2 Germany 3 India 11 Japan 1 Switzerland 1 United Kingdom 11 United States 35 Global 307
Changzhou Qinuo Chemical Co., Ltd.Co., Ltd.
Tel
0519-0519-83812535
Email
sales@qinuochem.com
Country
China
ProdList
287
Advantage
60
Liyang Kunlu biological technology co.,ltd
Tel
0519-87310015 13813530041
Fax
0519-87310015
Email
200601296@qq.com
Country
China
ProdList
173
Advantage
58
SiChuang NanBu Honesty Technology Co., Ltd.
Tel
0838-5675166 15883665058
Fax
0838-5675535
Email
nbcxkj@126.com
Country
China
ProdList
668
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Liaoning Tianhua Chemical Co., Ltd.
Tel
0418-6530555 2855550
Fax
+86-418-6502885
Country
China
ProdList
338
Advantage
69
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35906
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12458
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
More
Less

View Lastest Price from 2,5-Dichloropyrimidine manufacturers

R&D Scientific Inc.
Product
2,5-Dichloropyrimidine 22536-67-0
Price
US $1250.00/Kg
Min. Order
1Kg
Purity
98
Supply Ability
500 Kg
Release date
2024-04-26
Henan Fengda Chemical Co., Ltd
Product
2,5-Dichloropyrimidine 22536-67-0
Price
US $36.00-1.10/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08
Hebei Duling International Trade Co. LTD
Product
2,5-Dichloropyrimidine 22536-67-0
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 tons
Release date
2022-10-17

22536-67-0, 2,5-DichloropyrimidineRelated Search:

Thionyl chloride 4 6-DICHLOROPYRIMIDINE 99%,4,6-Dichloropyrimidine ,98% Sulfadiazine Dichloroethane 1,2-Dichloroethane 5-Fluorouracil Quinclorac Sodium dichloroisocyanurate 4-Amino-2,5,6-trichloropyrimidine 2,4,5,6-TETRACHLOROPYRIMIDINE 2-4-DICHLOROPYRIMIDINE CRYSTALLINE,2,4-DICHLOROPYRIMIDINE,2,4-Dichloropyrimidine, GC 97%,2,4-Dichloropyrimidine, 98+% 2-Amino-5-bromo-4,6-dichloropyrimidine 97%,2-Amino-5-bromo-4,6-dichloropyrimidine97% 2-Chloromethyl-4,6-dichloropyrimidine 5-Bromo-2,4-dichloropyrimidine ,97%,5-BROMO-2,4-DICHLOROPYRIMIDINE 99% 2,4-Dichloropyrimidine-5-carboxylic acid 5-Methyl-2,4-dichloropyrimidine Methyl 2,4-dichloropyrimidine-5-carboxylate, GC 97% 2,4,5-Trichloropyrimidine

  • 2,5-DICHLOROPYRIMIDINE
  • Pyrimidine, 2,5-dichloro- (7CI,8CI,9CI)
  • 2,5-DICHLOROPYRIMIDINE,PURITY:95% MIN(HPLC)
  • Pyrimidine, 2,5-dichloro-
  • 2,5-chloropyrimidine
  • 2,5-DichloropyriMidine 97+%
  • 2,5-Dichloro-1,3-diazine
  • 2,5-DichloropyriMidine 97+%, 5-DichloropyriMidine 97+%
  • 2,5-Dichloropyrimidine 97%
  • EOS-60492
  • 2,5‐Dichloropyridimidine
  • 2,5-Dichlo
  • 2,5-DICHLOROPYRIMIDINE,PURITY
  • Macitentan Impurity 32
  • 2,5-Dichloropyrimidine&gt
  • 22536-67-0
  • 84-73-3
  • 22536-60-0
  • Heterocycle-Pyrimidine series
  • Building Blocks
  • C4 to C5
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyrimidines
  • Chlorinated heterocyclic series
  • PYRIMIDINE
  • Pyrimidine Series
  • Pyridines, Pyrimidines, Purines and Pteredines