ChemicalBook > CAS DataBase List > AG 2263
AG 2263
- Product Name
- AG 2263
- CAS No.
- 638213-98-6
- Chemical Name
- AG 2263
- Synonyms
- AG 2263;AGL 2263;AGL 2263,AGL2263;Benzenepropanenitrile, α-[(2,3-dihydro-2-oxo-5-benzoxazolyl)methylene]-3,4-dihydroxy-β-oxo-, (αE)-
- CBNumber
- CB7828124
- Molecular Formula
- C17H10N2O5
- Formula Weight
- 322.27
- MOL File
- 638213-98-6.mol
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AG 2263 Property
- Melting point:
- 210 °C
- Density
- 1.541±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 2 mg/ml
- form
- A crystalline solid
- pka
- 7.47±0.20(Predicted)
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 21776
- Product name
- AGL 2263
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $68
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21776
- Product name
- AGL 2263
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $302
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21776
- Product name
- AGL 2263
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $535
- Updated
- 2024/03/01
AK Scientific
- Product number
- 3327CR
- Product name
- (E)-2-(3,4-Dihydroxybenzoyl)-3-(2-oxo-3H-1,3-benzoxazol-5-yl)prop-2-enenitrile
- Packaging
- 10mg
- Price
- $694
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0062886
- Product name
- AGL-2263
- Purity
- 95.80%
- Packaging
- 50mg
- Price
- $850
- Updated
- 2021/12/16
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AG 2263 Chemical Properties,Usage,Production
Uses
AGL-2263 is an insulin receptor and insulin-like growth factor (IGF) receptor inhibitor[1][2].
References
[1] Li Y, et al. GDM-associated insulin deficiency hinders the dissociation of SERT from ERp44 and down-regulates placental 5-HT uptake. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):E5697-705. DOI:10.1073/pnas.1416675112
[2] Hua Zhang, et al. Somatic cells initiate primordial follicle activation and govern the development of dormant oocytes in mice. Curr Biol. 2014 Nov 3;24(21):2501-8. DOI:10.1016/j.cub.2014.09.023
[3] Ying Han, et al. Insulin mitigates apoptosis of porcine follicular granulosa cells by downregulating BimEL. Reprod Biol. 2019 Sep;19(3):293-298. DOI:10.1016/j.repbio.2019.08.003
AG 2263 Preparation Products And Raw materials
Raw materials
Preparation Products
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