DEVAZEPIDE

Product Name: DEVAZEPIDE
CAS No.: 103420-77-5
Chemical Name: DEVAZEPIDE
Synonyms: 718;MK-329;L-364718;evazepide;DEVAZEPIDE;EVAZEPIDE, PANOS;Betaxolol Impurity 12;(3S)-1-Methyl-3-[(1H-indol-2-yl)carbonylamino]-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one;(S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide;N-[(3S)-2,3-DIHYDRO-1-METHYL-2-OXO-5-PHENYL-1H-1,4-BENZODIAZEPIN-3-YL]-1H-INDOLE-2-CARBOXAMIDE
CBNumber: CB7849798
Molecular Formula: C25H20N4O2
Formula Weight: 408.45
MOL File: 103420-77-5.mol

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DEVAZEPIDE Property

Boiling point:: 758.6±60.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: >5mg/mL
pka: 13.25±0.40(Predicted)
form: powder
color: white to off-white

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Safety

Hazard Codes: T+
Risk Statements: 28
Safety Statements: 28-36/37-45
RIDADR: UN 2811 6.1 / PGI
WGK Germany: 3
RTECS: NL5994460

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D3821
Product name: Devazepide
Purity: ≥98% (HPLC), powder
Packaging: 5mg
Price: $123.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: D3821
Product name: Devazepide
Purity: ≥98% (HPLC), powder
Packaging: 25mg
Price: $825
Updated: 2024/03/01

Tocris

Product number: 2304
Product name: Devazepide
Purity: ≥99%(HPLC)
Packaging: 50
Price: $1135
Updated: 2021/12/16

Tocris

Product number: 2304
Product name: Devazepide
Purity: ≥99%(HPLC)
Packaging: 10
Price: $270
Updated: 2021/12/16

Usbiological

Product number: 255128
Product name: Devazepide
Packaging: 10mg
Price: $531
Updated: 2021/12/16

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DEVAZEPIDE Chemical Properties,Usage,Production

Uses

Antagonist (cholecystokinin).

Uses

Devazepide has been used as a cholecystokinin receptor 1 (CCK1R) antagonist in human embryonic kidney 293T cells and in human pancreatic slices.

Definition

ChEBI: An indolecarboxamide obtained by formal condensation of the carboxy group of indole-2-carboxylic acid with the exocyclic amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one. A cholecystokinin antagonist used f r treatment of gastrointestinal disorders.

General Description

Devazepide is derived from asperlicin by chemical modification and has the benzodiazepine backbone.

Biochem/physiol Actions

Devazepide is a CCK1 (CCK-A) receptor antagonist and a CCK8 antagonist.

storage

Store at +4°C

DEVAZEPIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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DEVAZEPIDE Suppliers

China 15 Germany 1 United Kingdom 4 United States 11 Global 31

3B Pharmachem (Wuhan) International Co.,Ltd.

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Energy Chemical

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LEAPCHEM CO., LTD.

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Lanospharma Laboratories Co.,Ltd

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103420-77-5, DEVAZEPIDERelated Search:

Pranazepide N-(2-OXO-5-PHENYL-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-ACETAMIDE 3-AMINO-5-PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE DEVAZEPIDE tarazepide 3-AMINO-5-METHYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE

N-[(3S)-2,3-DIHYDRO-1-METHYL-2-OXO-5-PHENYL-1H-1,4-BENZODIAZEPIN-3-YL]-1H-INDOLE-2-CARBOXAMIDE

DEVAZEPIDE

EVAZEPIDE, PANOS

(3S)-1-Methyl-3-[(1H-indol-2-yl)carbonylamino]-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one

L-364718

MK-329

(S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide

1H-Indole-2-carboxamide, N-[(3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-

718

evazepide

Betaxolol Impurity 12

103420-77-5

C25H20N4O2