ChemicalBook > CAS DataBase List > 3-Nitrophthalic anhydride

3-Nitrophthalic anhydride

Product Name
3-Nitrophthalic anhydride
CAS No.
641-70-3
Chemical Name
3-Nitrophthalic anhydride
Synonyms
1,3-Isobenzofurandione, 4-nitro-;3-Nitrophthalic Acid Anhydride;4-NITRO-ISOBENZOFURAN-1,3-DIONE;NSC 4134;NSC 27006;3-NitrophthaL;Pomalidomide INT;Apremilast Impurity 90;Pomalidomide Impurity 36;3-NITROPHTHALIC ANHYDRIDE
CBNumber
CB8116378
Molecular Formula
C8H3NO5
Formula Weight
193.11
MOL File
641-70-3.mol
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3-Nitrophthalic anhydride Property

Melting point:
163-165 °C (lit.)
Boiling point:
329.3°C (rough estimate)
Density 
1.6392 (rough estimate)
refractive index 
1.4700 (estimate)
storage temp. 
Store below +30°C.
form 
Crystalline Powder
color 
Beige to yellow
Water Solubility 
MAY DECOMPOSE
Sensitive 
Moisture Sensitive
BRN 
179963
CAS DataBase Reference
641-70-3(CAS DataBase Reference)
NIST Chemistry Reference
3-Nitrophthalic anhydride(641-70-3)
EPA Substance Registry System
1,3-Isobenzofurandione, 4-nitro- (641-70-3)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
F 
10-21
TSCA 
Yes
HS Code 
29173980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.20903
Product name
3-Nitrophthalic anhydride
Purity
for synthesis
Packaging
25g
Price
$87.5
Updated
2024/03/01
Sigma-Aldrich
Product number
8.20903
Product name
3-Nitrophthalic anhydride
Purity
for synthesis
Packaging
100g
Price
$164
Updated
2024/03/01
Sigma-Aldrich
Product number
156884
Product name
3-Nitrophthalic anhydride
Purity
98%
Packaging
5g
Price
$76.2
Updated
2024/03/01
Sigma-Aldrich
Product number
156884
Product name
3-Nitrophthalic anhydride
Purity
98%
Packaging
25g
Price
$148.8
Updated
2024/03/01
TCI Chemical
Product number
N0245
Product name
3-Nitrophthalic Anhydride
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$33
Updated
2024/03/01
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3-Nitrophthalic anhydride Chemical Properties,Usage,Production

Chemical Properties

Beige to yellow crystalline powder

Uses

An intermediate for the synthesis of a benzimidazole PARP inhibitor I (succinate salt) (ABT-472). Reactions with aminoquinazolinones yield phthalimidoquinazolinones.

Uses

4-Nitrophthalic Anhydride is an intermediate for the synthesis of the benzimidazole PARP inhibitor I, ABT-472. It reacts with aminoquinazolinones to yield phthalimidoquinazolinones.

Preparation

3-Nitrophthalic anhydride can be prepared by heating 3-nitrophthalic acid under various conditions and by the action of acetic anhydride, essentially as in the procedure described. The direct nitration of phthalic anhydride yields 3-nitrophthalic anhydride together with the isomeric 4-nitro compound.

Purification Methods

Crystallise it from *C6H6, *C6H6/pet ether, Me2CO, AcOH, or Ac2O (m 164-165o). Dry it at 100o. [Beilstein 17 III/IV 6149, 17/11 V 266.]

3-Nitrophthalic anhydride Preparation Products And Raw materials

Raw materials

3-Nitrophthalic acid

Preparation Products

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3-Nitrophthalic anhydride Suppliers

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View Lastest Price from 3-Nitrophthalic anhydride manufacturers

Hebei Kangcang new material Technology Co., LTD
Product
3-Nitrophthalic anhydride 641-70-3
Price
US $9.00-80.00/g
Min. Order
10g
Purity
min99%
Supply Ability
10 tons
Release date
2024-03-26
Asia Chem I and E (Jiangsu) Co Ltd
Product
3-Nitrophthalic anhydride 641-70-3
Price
US $62.79/Kg/Drum
Min. Order
25Kg/Drum
Purity
98.00%HPLC
Supply Ability
8.8tons/month
Release date
2021-09-23
Hebei Guanlang Biotechnology Co,.LTD
Product
3-Nitrophthalic anhydride 641-70-3
Price
US $10.70/Kg/Bag
Min. Order
10g
Purity
99%
Supply Ability
10000kg
Release date
2021-08-19

641-70-3, 3-Nitrophthalic anhydrideRelated Search:

3-Fluorophthalic anhydride 4-BROMO PHTHALIC ANHYDRUS Dimethyl phthalate cis-1,2,3,6-Tetrahydrophthalic anhydride Isatoic Anhydride 2-Nitrobenzoic acid 2-Nitrobenzaldehyde CIS-BUTENEDIOIC ANHYDRIDE PHTHALAMIDE O-Phthalimide Dibutyl phthalate Phthalonitrile Phthalic anhydride 3-Nitrophthalic acid 3-Nitrophthalhydrazide 3-Nitrophthalimide METHYL 2-NITROBENZOATE 3-(METHOXYMETHYL)ANILINE

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  • C8H3NO5
  • O2NC6H3CO2O
  • Organic Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acid Anhydrides
  • Building Blocks
  • Anhydride Monomers
  • Monomers
  • Polymer Science
  • Carbonyl Compounds
  • Carboxylic Acid Anhydrides
  • Organic Building Blocks
  • Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acid Anhydrides
  • Chemical Synthesis
  • Organic Building Blocks
  • Amines
  • Aromatics
  • Intermediates
  • Phthalic Acids, Esters and Derivatives
  • Dyes intermediates