Aldesulfone Sodium
- Product Name
- Aldesulfone Sodium
- CAS No.
- 144-75-2
- Chemical Name
- Aldesulfone Sodium
- Synonyms
- NSC 27222;Novotrone;Aldesulfone;Diasone sodium;SodiuM sulfoxone;Adesulfone Sodium;Aldesulfone Sodium;Sulfoxone disodium;SodiuM aldesulphone;URZHNIBXZDLLSY-UHFFFAOYSA-N
- CBNumber
- CB81177969
- Molecular Formula
- C14H14N2Na2O6S3
- Formula Weight
- 0
- MOL File
- 144-75-2.mol
Aldesulfone Sodium Property
- Melting point:
- 263-265 °C (decomp)
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White
- Stability:
- Stable. Incompatible with strong oxidizing agents.
Safety
- Toxicity
- LD50 oral in mouse: 10gm/kg
N-Bromosuccinimide Price
- Product number
- S673025
- Product name
- SodiumSulfoxone(90%)
- Packaging
- 100mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- API0008928
- Product name
- SULFOXONE SODIUM
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.85
- Updated
- 2021/12/16
- Product number
- 48693
- Product name
- SodiumSulfoxone
- Packaging
- 10g
- Price
- $2120
- Updated
- 2021/12/16
Aldesulfone Sodium Chemical Properties,Usage,Production
Originator
Diasone Sodium,Abbott,US,1947
Uses
Sodium Sulfoxone is used in tuberculosis therapy along with Streptomycin (S687500).
Manufacturing Process
About 20 grams of diamino diphenyl sulfone is dissolved in about 500 cc of ethyl alcohol (3A made up of 5 parts methyl alcohol and 100 parts of ethyl alcohol) by placing the ingredients in a flask provided with a reflux condenser and warming over a water bath. About 24 grams of pure grade, very finely powdered (40 to 60 mesh) sodium formaldehyde sulfoxylate is then rapidly added to the alcohol solution of diamino diphenyl sulfone and the mixture refluxed in the usual manner. It was found that the mixture should be refluxed for a total of 5 hours and that a precipitate starts to form near the 3 hour period. The reaction mixture is then cooled to 15°C and kept at this temperature for about 1 hour. The precipitate formed in the filtrate is filtered off rapidly and drained as much as possible to remove mother liquor and then washed with small amounts of cold alcohol. The solid product is immediately placed in a desiccator and dried over sulfuric acid for about 20 hours.
Therapeutic Function
Antibacterial (leprostatic)
Aldesulfone Sodium Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Aldesulfone Sodium manufacturers
- Product
- Aldesulfone Sodium 144-75-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-07-16
- Product
- Adesulfone Sodium 144-75-2
- Price
- US $0.01-1.00/KG
- Min. Order
- 25KG
- Purity
- 99%min
- Supply Ability
- 20 tons
- Release date
- 2020-05-08