2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE Property

Boiling point:

120 °C(Press: 0.3 Torr)

Density 

1.249 g/cm3

storage temp. 

Store at -20°C

solubility 

DMF: 30 mg/ml; DMSO: 15 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 1 mg/ml

pka

1.79±0.40(Predicted)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE Chemical Properties,Usage,Production

Description

EMPO is a hydrophilic cyclic nitrone analog of the free radical spin trap DMPO . The EMPO-superoxide adduct (EMPO-OOH) exhibits an ESR spectrum that is similar to the DMPO-OOH spectrum. However, the EMPO-OOH adduct is about 5-8 times more stable (t_1/2 = 4.8 – 8.6 min) and does not spontaneously decay to the hydroxyl adduct, making spectral interpretation less difficult.