ChemicalBook > CAS DataBase List > 5-BROMO-6-HYDROXYNICOTINIC ACID

5-BROMO-6-HYDROXYNICOTINIC ACID

Product Name: 5-BROMO-6-HYDROXYNICOTINIC ACID
CAS No.: 41668-13-7
Chemical Name: 5-BROMO-6-HYDROXYNICOTINIC ACID
Synonyms: 5-Bromo-6-Hydroxy Niacin;5-BROMO-6-HYDROXYNICOTINIC ACID;6-Hydroxy-5-bromonicotinic acid;3-BROMO-5-CARBOXY-2(1H)-PYRIDINONE;5-Bromo-6-hydroxynicotinic acid 97%;5-Bromo-6-hydroxynicotinic acid ,97%;5-BROMO-6-HYDROXYPYRIDINE-3-CARBOXYLIC ACID;5-BROMO-6-HYDROXY-3-PYRIDINECARBOXYLIC ACID;5-bromo-6-oxo-1H-pyridine-3-carboxylic acid;5-Bromo-6-hydroxy-pyridin-3-carboxylic acid
CBNumber: CB8137629
Molecular Formula: C6H4BrNO3
Formula Weight: 218
MOL File: 41668-13-7.mol

Less

5-BROMO-6-HYDROXYNICOTINIC ACID Property

Melting point:: >300
Boiling point:: 348.1±42.0 °C(Predicted)
Density: 2.015±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 3.38±0.50(Predicted)
form: powder to crystal
color: White to Almost white
InChI: InChI=1S/C6H4BrNO3/c7-4-1-3(6(10)11)2-8-5(4)9/h1-2H,(H,8,9)(H,10,11)
InChIKey: PQDLYKZCJBGXPQ-UHFFFAOYSA-N
SMILES: C1NC(=O)C(Br)=CC=1C(O)=O

Less

Safety

Hazard Codes: Xi,Xn
Risk Statements: 22
Hazard Note: Irritant/Keep Cold
HazardClass: IRRITANT
HS Code: 29333990

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: B5193
Product name: 5-Bromo-6-hydroxynicotinic Acid
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $57
Updated: 2025/07/31

TCI Chemical

Product number: B5193
Product name: 5-Bromo-6-hydroxynicotinic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $172
Updated: 2025/07/31

TRC

Product number: B696223
Product name: 5-Bromo-6-hydroxynicotinic Acid
Packaging: 1g
Price: $75
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0024564
Product name: 5-BROMO-6-HYDROXYNICOTINIC ACID
Purity: 95.00%
Packaging: 1G
Price: $642.99
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB147581
Product name: 5-Bromo-6-oxo-1,6-dihydro-3-pyridinecarboxylicacid
Packaging: 1g
Price: $283
Updated: 2021/12/16

Less

5-BROMO-6-HYDROXYNICOTINIC ACID Chemical Properties,Usage,Production

Chemical Properties

Light green solid

Synthesis

5006-66-6

41668-13-7

Synthesis of 5-bromo-6-hydroxynicotinic acid: 6-hydroxynicotinic acid (8 g, 57.6 mmol) was suspended in water (30 mL) and bromine (4.2 mL, 81.4 mmol) was slowly added under ice bath cooling conditions. After addition, the reaction mixture was stirred at room temperature for 24 hours. Upon completion of the reaction, the solid product was collected by filtration, washed with water and dried in a vacuum oven at 40 °C for 24 h to afford 5-bromo-6-hydroxynicotinic acid (12.1 g, 97% yield) as a tan solid. The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 8.04 (d, J = 2.53 Hz, 1H), 8.16 (d, J = 2.27 Hz, 1H), 12.59 (br s, 1H), 12.90 (br s, 1H).

References

[1] Journal of Medicinal Chemistry, 2013, vol. 56, # 24, p. 9874 - 9896
[2] Journal of Medicinal Chemistry, 2005, vol. 48, # 15, p. 4892 - 4909
[3] Patent: WO2007/70818, 2007, A1. Location in patent: Page/Page column 103
[4] Patent: WO2006/88919, 2006, A2. Location in patent: Page/Page column 134-135
[5] Patent: US2008/85906, 2008, A1. Location in patent: Page/Page column 15

5-BROMO-6-HYDROXYNICOTINIC ACID Preparation Products And Raw materials

Raw materials

2-Hydroxy-5-pyridinecarboxylic acid Bromine Sodium metabisulfite

Preparation Products

Less

5-BROMO-6-HYDROXYNICOTINIC ACID Suppliers

Americas 1 China 144 Czech Republic 1 Europe 1 Germany 4 India 9 Japan 1 United Kingdom 5 United States 16 Global 182

Shanghai Carlow Chemicals Co., Ltd.

Tel: 21-33526724 18930996265
Fax: 37023730
Email: info@carlowchem.com
Country: China
ProdList: 1922
Advantage: 58

Sanjing New Materials Technology (Taizhou) Co., Ltd.

Tel: 15250805028
Fax: QQ：1048979734
Email: 1048979734@qq.com
Country: China
ProdList: 339
Advantage: 58

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Wuhan Arike Technology Co., Ltd.

Tel: 027- 51832457 94518350
Fax: E-Mail Inquiry
Country: China
ProdList: 746
Advantage: 62

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 7247
Advantage: 62

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 6387
Advantage: 52

Chengdu HappySyn Pharmaceutical Technology Co., Ltd.

Tel: 028-85114309 18982182443
Email: yangli@happysyn.com
Country: China
ProdList: 2150
Advantage: 55

Shanghai ZaiQi Bio-Tech Co., Ltd.

Tel: 021-54824098, 021-37212705 021-37212706, 13391256916
Fax: 021-54824069
Email: sales@chemzq.com
Country: China
ProdList: 570
Advantage: 55

Suzhou Sibian Chemical Technology Co.,Ltd.

Tel: 0512-65617459 18915409046
Fax: 0512-65617459
Email: sales@sibian-chem.com
Country: China
ProdList: 1922
Advantage: 55

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Bsisun HK Imoprt And Export Company Limited

Tel: +86-18068513926
Fax: 0086-519-85153711
Country: China
ProdList: 1277
Advantage: 55

Cantotech Chemicals, Ltd.

Tel: 86-0755-86635001
Fax: 86-0755-22642228
Email: cantotech@126.com
Country: China
ProdList: 4566
Advantage: 55

Chimica Laboratories Co., Ltd

Tel: 0086-573-82585213
Fax: 0086-573-82585233
Email: bai@chimicalabs.com
Country: China
ProdList: 861
Advantage: 64

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 42446
Advantage: 60

Shanghai Yongye Biotechnology Co., Ltd.

Tel: 86-021-61559134 15921386130
Fax: 021-55068248
Email: 3423497944@qq.com
Country: China
ProdList: 8144
Advantage: 55

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9756
Advantage: 58

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Tianjing Geneston Bio-tech Co.,Ltd.

Tel: 022-60131465 18920720807
Fax: 022-58558581
Email: zishan_1986@163.com
Country: China
ProdList: 743
Advantage: 58

Bellen Chemistry Co., Ltd.

Tel: 010-60400365-8001 15910885229
Fax: 010-60400361
Email: service@bellenchem.com
Country: China
ProdList: 4514
Advantage: 60

Shanghai Boyners Pharm-Tech Co., Ltd.

Tel: 13817873692
Fax: 021-31329586
Email: mkt@boynerspharm.com
Country: China
ProdList: 1707
Advantage: 55

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7992
Advantage: 55

Jiaxing Rich Biological Technology Co., Ltd.

Tel: 0573-11111111-1111 18969316891
Fax: -
Email: richmol@163.com
Country: China
ProdList: 449
Advantage: 50

Wuhan Chemwish Technology Co.， Ltd

Tel: 027-67849912
Fax: 027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 9148
Advantage: 60

Tianjin Wizard Science and Technology Co., Ltd.

Tel: 22-22-58620773 18102163693
Fax: 86-22-58620773
Email: tjchemwizard@163.com
Country: China
ProdList: 94
Advantage: 55

skychemical Co.Ltd

Tel: 021-20960837,QQ1332204249
Fax: 021-20960837
Email: sales@skychemical.com
Country: China
ProdList: 3341
Advantage: 55

Nanjing Vital Chemical Co., Ltd.

Tel: 025-87193546 18652950785
Fax: 025-87193546
Email: chemweiao@163.com
Country: China
ProdList: 9021
Advantage: 60

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9627
Advantage: 58

Shanghai Haozhixiang Biotechnology Co., Ltd

Tel: 526763801 13301653310
Fax: +86-21-51619052
Email: 526763801@qq.com
Country: China
ProdList: 9273
Advantage: 55

Henan CoreyChem Co., Ltd

Tel: 0371-86658258
Fax: 0371-60996044
Email: info@coreychem.com
Country: China
ProdList: 10453
Advantage: 58

Shanghai Qiao Chemical Science Co., Ltd

Tel: 021-58892003
Email: info@qiaochem.com
Country: China
ProdList: 6059
Advantage: 65

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Beijing Hechemist Technology CO.,LTD

Tel: 18511709189
Fax: 010-58043593
Email: sales@hechemist.com
Country: China
ProdList: 2835
Advantage: 58

ChengDu TongChuangYuan Pharmaceutical Co.Ltd

Tel: 028-83379370 13880556291
Fax: 028-87747383
Email: tcy@tcypharm.com
Country: China
ProdList: 7218
Advantage: 58

Shanghai SuperLan Chemcial Technique Centre

Tel: 0-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
ProdList: 12476
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Jiangsu C-jun Biotechnology Co., Ltd.

Tel: +86 (519) 8969-7536
Fax: +86 (519) 8988-9226
Email: sales3@cjxrpharm.com
Country: China
ProdList: 217
Advantage: 58

Shanghai Kangman Biological Technology Co., Ltd.

Tel: 18800375331
Fax: 021-50908862
Email: kangmansales@163.com
Country: China
ProdList: 7570
Advantage: 55

Shanghai Jinsheng Pharmaceutical Co., Ltd.

Tel: 1365-13651960330 13651960330
Email: xiangfeixia@jspharmatech.com
Country: China
ProdList: 356
Advantage: 58

Dalian lichuang Chemical Co., Ltd

Tel: 0411-0411-00000000 13644282108
Fax: -
Email: 3500508746@qq.com
Country: China
ProdList: 2896
Advantage: 55

Less

View Lastest Price from 5-BROMO-6-HYDROXYNICOTINIC ACID manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 5-BROMO-6-HYDROXYNICOTINIC ACID 41668-13-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-06-24

Hebei Chuanghai Biotechnology Co., Ltd

Product: 5-BROMO-6-HYDROXYNICOTINIC ACID 41668-13-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-30

Henan Fengda Chemical Co., Ltd

Product: 5-BROMO-6-HYDROXYNICOTINIC ACID 41668-13-7
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-09

41668-13-7, 5-BROMO-6-HYDROXYNICOTINIC ACIDRelated Search:

METHYL 5-BROMO-6-HYDROXYNICOTINATE ethyl 5-broMo-6-hydroxynicotinate 1,2,3,4-TETRAHYDROQUINOLIN-6-OL 6H-Pyrrolo[2,3-b]pyridin-6-one, 1,7-dihydro- 5-Iodo-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid Methyl ester 5-Bromonicotinic acid 5-BROMO-2-HYDROXYNICOTINIC ACID,5-Bromo-2-hydroxynicotinic acid 98%,5-BROMO-2-HYDROXYNICOTINIC ACID HPLC 99%,5-Bromo-2-hydroxynicotinic acid ,98% 5-BROMO-6-HYDROXYNICOTINIC ACID 5-bromo-6-(cyclopropylmethoxy)nicotinic acid 1-BENZYL-5-BROMO-6-OXO-1,6-DIHYDRO-3-PYRIDINECARBOXYLIC ACID 5-bromo-6-(tetrahydro-2h-pyran-4-yloxy)nicotinic acid METHYL 5-BROMO-6-OXO-1,6-DIHYDRO-3-PYRIDINECARBOXYLATE 5-bromo-6-(cyclohexyloxy)nicotinic acid 6-(2-aziridin-1-ylethoxy)-5-bromonicotinic acid ethyl 3-bromo-4-oxo-4H-quinolizine-1-carboxylate 5-bromo-6-(piperidin-4-yloxy)nicotinic acid 5-BROMO-2,6-DIMETHOXY-NICOTINIC ACID METHYL ESTER 5-bromo-6-(piperidin-4-ylmethoxy)nicotinic acid

5-Bromo-6-hydroxynicotinic acid ,97%

6-Hydroxy-5-bromonicotinic acid

5-broMo-6-oxo-1,6-dihydropyridine-3-carboxylic acid

5-broMo-1,6-dihydro-6-oxo-3-Pyridinecarboxylic acid

5-BROMO-6-HYDROXY-3-PYRIDINECARBOXYLIC ACID

5-BROMO-6-HYDROXYNICOTINIC ACID

5-BROMO-6-HYDROXYPYRIDINE-3-CARBOXYLIC ACID

3-BROMO-5-CARBOXY-2(1H)-PYRIDINONE

5-Bromo-6-hydroxynicotinic acid 97%

3-Pyridinecarboxylic acid, 5-bromo-1,6-dihydro-6-oxo-

5-BROMO-6-HYDROXYNICOTINIC ACID ISO 9001：2015 REACH

5-bromo-6-oxo-1H-pyridine-3-carboxylic acid

5-Bromo-6-Hydroxy Niacin

5-Bromo-6-hydroxy-pyridin-3-carboxylic acid

41668-13-7

Carboxylic Acids

blocks

Bromides

Carboxes

Pyridines

Carboxylic Acids

API intermediates

Pyridine