3-Bromo-4-chloropyridine
- Product Name
- 3-Bromo-4-chloropyridine
- CAS No.
- 36953-42-1
- Chemical Name
- 3-Bromo-4-chloropyridine
- Synonyms
- 4-CHLORO-3-BROMOPYRIDINE;3-BROMO-4-CHLOROPYRIDINE;3-BroMo-4-chloridepyridine;Pyridine, 3-bromo-4-chloro-;3-Bromo-4-chloropyridine,98%;3-broMo -4-chlorine pyridine;3-BroMo-2-chloropyridine, 97+%;3-BroMo-4-chloropyridine, 98% 1GR;3-Bromo-4-chloropyridine ISO 9001：2015 REACH;TIANFUCHEM--36953-42-1--3-Bromo-4-chloropyridine in stock
- CBNumber
- CB8138363
- Molecular Formula
- C5H3BrClN
- Formula Weight
- 192.44
- MOL File
- 36953-42-1.mol
3-Bromo-4-chloropyridine Property
- Melting point:
- 17.5-18.5 °C
- Boiling point:
- 115 °C(Press: 20 Torr)
- Density
- 1.19
- refractive index
- 1.453
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- form
- Liquid After Melting
- pka
- 1.74±0.10(Predicted)
- color
- Clear colorless to yellow
- InChI
- InChI=1S/C5H3BrClN/c6-4-3-8-2-1-5(4)7/h1-3H
- InChIKey
- QADXKWUCCGPQNR-UHFFFAOYSA-N
- SMILES
- C1=NC=CC(Cl)=C1Br
- CAS DataBase Reference
- 36953-42-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi,T
- Risk Statements
- 36/37/38-20/22-41-37/38-25
- Safety Statements
- 36/37/39-26-22-45-39
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CDS003116
- Product name
- 3-Bromo-4-chloropyridine
- Purity
- Aldrich<SUP>CPR</SUP>
- Packaging
- 250 mg
- Price
- $73.1
- Updated
- 2025/07/31
- Product number
- B684388
- Product name
- 3-Bromo-4-chloropyridine
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- B684388
- Product name
- 3-Bromo-4-chloropyridine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- N150
- Product name
- 3-Bromo-4-chloropyridine
- Packaging
- 5g
- Price
- $23
- Updated
- 2021/12/16
- Product number
- 024993
- Product name
- 3-Bromo-4-chloropyridine
- Purity
- 98%
- Packaging
- 5g
- Price
- $26
- Updated
- 2021/12/16
3-Bromo-4-chloropyridine Chemical Properties,Usage,Production
Chemical Properties
Light yellow needles
Uses
3-Bromo-4-chloropyridine can be used as a bulk drug intermediate in pharmaceutical synthesis.
Synthesis
31270-80-1
36953-42-1
220939-72-0
Example 543A Synthesis of 3-bromo-4-chlorofuro[3,2-c]pyridine: 4-Chlorofuro[3,2-c]pyridine (commercially available, 10.60 g, 69 mmol) was dissolved in carbon tetrachloride (135 mL) and cooled to -15°C. Bromine (12.13 g, 80 mmol) was added dropwise over 15 min. The reaction mixture was stirred at room temperature for 18 hours. Upon completion of the reaction, the solvent was removed under vacuum. The residue was dissolved in methanol (250 mL), 20% aqueous sodium hydroxide solution (35 mL) was added and stirring was continued for 1 hour at room temperature. Subsequently, methanol was removed under vacuum and the residue was partitioned between water (100 mL) and dichloromethane (50 mL). The organic layers were combined, dried over anhydrous magnesium sulfate, and the solvent was removed in vacuo to afford 3-bromo-4-chlorofuro[3,2-c]pyridine 15.45 g (96% yield) as a solid. Mass spectrum (ESI(+)) m/e 232,234 (M + H)+.
References
[1] Patent: US2005/26944, 2005, A1
3-Bromo-4-chloropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Bromo-4-chloropyridine manufacturers
- Product
- 3-Bromo-4-chloropyridine 36953-42-1
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100 mt
- Release date
- 2024-12-03
- Product
- 3-Bromo-2-chloropyridine 36953-42-1
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30
- Product
- 3-Bromo-4-chloropyridine 36953-42-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-03