ChemicalBook > CAS DataBase List > N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea

N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea

Product Name
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea
CAS No.
330796-24-2
Chemical Name
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea
Synonyms
Hedgehog Antagonist VII;Hedgehog Antagonist VIII;1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[[3-(4-fluorophenyl)-4-oxo-quinazolin-2-yl]methyl]urea;1-(4-chloro-3-trifluoroMethyl-phenyl)-3-[3-(4-fluoro-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-ylMethyl]-urea;N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea;N-[4-Chloro-3-(trifluoromethyl)phenyl]-N’-[[3-(4-fluorophenyl)-3,4-dihydro\n-4-oxo-2-quinazolinyl]methyl]urea;Urea, N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]-
CBNumber
CB81873227
Molecular Formula
C23H15ClF4N4O2
Formula Weight
490.84
MOL File
330796-24-2.mol
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N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea Property

Density 
1.46±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMF:PBS(pH7.2) (1:2): 0.3 mg/ml; DMSO: 25 mg/ml; Ethanol: 10 mg/ml
form 
A crystalline solid
pka
12.17±0.46(Predicted)
color 
clear slightly yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16097
Product name
Hedgehog Antagonist VIII
Purity
≥98%
Packaging
500μg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
16097
Product name
Hedgehog Antagonist VIII
Purity
≥98%
Packaging
1mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
16097
Product name
Hedgehog Antagonist VIII
Purity
≥98%
Packaging
5mg
Price
$217
Updated
2024/03/01
Cayman Chemical
Product number
16097
Product name
Hedgehog Antagonist VIII
Purity
≥98%
Packaging
10mg
Price
$359
Updated
2024/03/01
TRC
Product number
C421960
Product name
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N’-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea
Packaging
10mg
Price
$255
Updated
2021/12/16
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N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea Chemical Properties,Usage,Production

Uses

A potent modulator of Hedgehog (Hh) protein function; a nanomolar Hh antagonist.

N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea Preparation Products And Raw materials

Raw materials

Preparation Products

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N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea Suppliers

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330796-24-2, N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]ureaRelated Search:


  • N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea
  • 1-(4-chloro-3-trifluoroMethyl-phenyl)-3-[3-(4-fluoro-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-ylMethyl]-urea
  • 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[[3-(4-fluorophenyl)-4-oxo-quinazolin-2-yl]methyl]urea
  • Hedgehog Antagonist VIII
  • N-[4-Chloro-3-(trifluoromethyl)phenyl]-N’-[[3-(4-fluorophenyl)-3,4-dihydro\n-4-oxo-2-quinazolinyl]methyl]urea
  • Hedgehog Antagonist VII
  • Urea, N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]-
  • 330796-24-2
  • C23H15ClF4N4O2
  • Aromatics
  • Heterocycles
  • Inhibitors