(4-Chloro-pyriMidin-2-yl)-diMethyl-aMine
- Product Name
- (4-Chloro-pyriMidin-2-yl)-diMethyl-aMine
- CAS No.
- 23631-02-9
- Chemical Name
- (4-Chloro-pyriMidin-2-yl)-diMethyl-aMine
- Synonyms
- 4-Chloro-2-(dimethylamino)pyrimidine;4-Chloro-N,N-diMethylpyriMidin-2-aMine;2-Pyrimidinamine, 4-chloro-N,N-dimethyl-;(4-Chloro-pyriMidin-2-yl)-diMethyl-aMine
- CBNumber
- CB82575254
- Molecular Formula
- C6H8ClN3
- Formula Weight
- 157.6
- MOL File
- 23631-02-9.mol
(4-Chloro-pyriMidin-2-yl)-diMethyl-aMine Property
- Boiling point:
- 248.9±32.0 °C(Predicted)
- Density
- 1.252±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 3.83±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- C368955
- Product name
- 4-Chloro-N,N-dimethylpyrimidin-2-amine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- J96447
- Product name
- (4-Chloro-pyrimidin-2-yl)-dimethyl-amine
- Packaging
- 100mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- 34197
- Product name
- 4-chloro-N,N-dimethylpyrimidin-2-amine
- Purity
- 97%
- Packaging
- 1g
- Price
- $850
- Updated
- 2021/12/16
- Product number
- A273539
- Product name
- 4-Chloro-N,N-dimethylpyrimidin-2-amine
- Purity
- 97%
- Packaging
- 1g
- Price
- $292
- Updated
- 2021/12/16
- Product number
- CD11161139
- Product name
- 4-Chloro-N,N-dimethylpyrimidin-2-amine
- Purity
- 97%
- Packaging
- 1g
- Price
- $392
- Updated
- 2021/12/16
(4-Chloro-pyriMidin-2-yl)-diMethyl-aMine Chemical Properties,Usage,Production
Synthesis
3934-20-1
74-89-5
31058-81-8
23631-02-9
Step B: Synthesis of 2-chloro-N,N-dimethylpyrimidin-4-amine. To a solution of 2,4-dichloropyrimidine (15.0 g, 10.15 mmol) in tetrahydrofuran (THF, 150 mL) was slowly added 50% aqueous methylamine (MeNH2) (22.7 g, 25.2 mmol). The reaction mixture was stirred at room temperature for 2 hours. After completion of the reaction, the reaction solution was poured into saturated aqueous sodium bicarbonate (NaHCO3) solution and the aqueous phase was extracted three times with chloroform (CHCl3). The organic layers were combined, dried with anhydrous magnesium sulfate (MgSO4), filtered and concentrated. The crude product was purified by fast chromatography (amino silica gel column, 20% ethyl acetate/hexane as eluent) to afford 2-chloro-N,N-dimethylpyrimidin-4-amine (8.66 g, 55% yield) and 4-chloro-N,N-dimethylpyrimidin-2-amine (0.87 g, 6% yield), both as white solids.
References
[1] Patent: EP1464335, 2004, A2. Location in patent: Page/Page column 172
(4-Chloro-pyriMidin-2-yl)-diMethyl-aMine Preparation Products And Raw materials
Raw materials
Preparation Products
(4-Chloro-pyriMidin-2-yl)-diMethyl-aMine Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from (4-Chloro-pyriMidin-2-yl)-diMethyl-aMine manufacturers
- Product
- (4-Chloro-pyriMidin-2-yl)-diMethyl-aMine 23631-02-9
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 95%min
- Supply Ability
- 20kg/month
- Release date
- 2019-12-19